Genomic Profiling of a Case of Glioneuronal Tumor with Neuropil-like Islands.
Acta Med Okayama
; 76(4): 473-477, 2022 Aug.
Article
in En
| MEDLINE
| ID: mdl-36123163
ABSTRACT
Glioneuronal tumor with neuropil-like islands (GNTNI) is a very rare subtype of glioneuronal tumor. We present a case of a 62-year-old man with GNTNI. Two adjacent lesions in the left parietal lobe were removed by left parietal craniotomy. The histological findings were glial cell proliferation and scattered rosettes consisting of synaptophysin-positive and NeuN-positive cells, leading to the diagnosis of GNTNI. Target sequencing revealed a genetic alteration similar to glioblastoma, IDH-wild type, which suggested adjuvant therapies. There are few previous reports on the treatment of this disease, and the patient should be followed carefully.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Brain Neoplasms
Limits:
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Acta Med Okayama
Year:
2022
Type:
Article