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Hyperactivation of mTORC1 in a double hit mutant zebrafish model of tuberous sclerosis complex causes increased seizure susceptibility and neurodevelopmental abnormalities.
De Meulemeester, Ann-Sofie; Heylen, Lise; Siekierska, Aleksandra; Mills, James D; Romagnolo, Alessia; Van Der Wel, Nicole N; Aronica, Eleonora; de Witte, Peter A M.
Affiliation
  • De Meulemeester AS; Laboratory for Molecular Biodiscovery, KU Leuven, Leuven, Belgium.
  • Heylen L; Laboratory for Molecular Biodiscovery, KU Leuven, Leuven, Belgium.
  • Siekierska A; Laboratory for Molecular Biodiscovery, KU Leuven, Leuven, Belgium.
  • Mills JD; Department of (Neuro)Pathology Amsterdam Neuroscience, Amsterdam UMC Location University of Amsterdam, Amsterdam, Netherlands.
  • Romagnolo A; Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.
  • Van Der Wel NN; Chalfont Centre for Epilepsy, Chalfont St Peter, United Kingdom.
  • Aronica E; Department of (Neuro)Pathology Amsterdam Neuroscience, Amsterdam UMC Location University of Amsterdam, Amsterdam, Netherlands.
  • de Witte PAM; Department of Medical Biology, Electron Microscopy Center Amsterdam, Amsterdam UMC Location University of Amsterdam, Amsterdam, Netherlands.
Front Cell Dev Biol ; 10: 952832, 2022.
Article in En | MEDLINE | ID: mdl-36238691
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Etiology_studies Language: En Journal: Front Cell Dev Biol Year: 2022 Type: Article Affiliation country: Belgium
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Etiology_studies Language: En Journal: Front Cell Dev Biol Year: 2022 Type: Article Affiliation country: Belgium