Activation of the Chemokine Receptor CCR1 and Preferential Recruitment of G&#945;i Suppress RSV Replication: Implications for Developing Novel Respiratory Syncytial Virus Treatment Strategies.

Li, Jiao; Xue, Ling; Wang, Jiachao; Meng, Aihong; Qiao, Jiajun; Li, Miao; Wang, Xiuli; Meng, Lingtong; Ning, Jingyuan; Gao, Xue; Li, Wenjian; Ma, Cuiqing; Wei, Lin

Activation of the Chemokine Receptor CCR1 and Preferential Recruitment of Gαi Suppress RSV Replication: Implications for Developing Novel Respiratory Syncytial Virus Treatment Strategies.

Li, Jiao; Xue, Ling; Wang, Jiachao; Meng, Aihong; Qiao, Jiajun; Li, Miao; Wang, Xiuli; Meng, Lingtong; Ning, Jingyuan; Gao, Xue; Li, Wenjian; Ma, Cuiqing; Wei, Lin.

Affiliation

Li J; Department of Immunology, Key Laboratory of Immune Mechanism and Intervention on Serious Disease in Hebei Province, Hebei Medical Universitygrid.256883.2, Shijiazhuang, China.
Xue L; Clinical Laboratory, Hebei Key Laboratory of Laboratory Medicine, the Second Hospital of Hebei Medical Universitygrid.256883.2, Shijiazhuang, China.
Wang J; Department of Immunology, Key Laboratory of Immune Mechanism and Intervention on Serious Disease in Hebei Province, Hebei Medical Universitygrid.256883.2, Shijiazhuang, China.
Meng A; Department of Immunology, Key Laboratory of Immune Mechanism and Intervention on Serious Disease in Hebei Province, Hebei Medical Universitygrid.256883.2, Shijiazhuang, China.
Qiao J; Respiratory Medicine, the Second Hospital of Hebei Medical Universitygrid.256883.2, Shijiazhuang, China.
Li M; Department of Immunology, Key Laboratory of Immune Mechanism and Intervention on Serious Disease in Hebei Province, Hebei Medical Universitygrid.256883.2, Shijiazhuang, China.
Wang X; Department of Immunology, Key Laboratory of Immune Mechanism and Intervention on Serious Disease in Hebei Province, Hebei Medical Universitygrid.256883.2, Shijiazhuang, China.
Meng L; Department of Immunology, Key Laboratory of Immune Mechanism and Intervention on Serious Disease in Hebei Province, Hebei Medical Universitygrid.256883.2, Shijiazhuang, China.
Ning J; Clinical Laboratory, Hebei Key Laboratory of Laboratory Medicine, the Second Hospital of Hebei Medical Universitygrid.256883.2, Shijiazhuang, China.
Gao X; Department of Immunology, Key Laboratory of Immune Mechanism and Intervention on Serious Disease in Hebei Province, Hebei Medical Universitygrid.256883.2, Shijiazhuang, China.
Li W; Department of Immunology, Key Laboratory of Immune Mechanism and Intervention on Serious Disease in Hebei Province, Hebei Medical Universitygrid.256883.2, Shijiazhuang, China.
Ma C; Department of Immunology, Key Laboratory of Immune Mechanism and Intervention on Serious Disease in Hebei Province, Hebei Medical Universitygrid.256883.2, Shijiazhuang, China.
Wei L; Department of Immunology, Key Laboratory of Immune Mechanism and Intervention on Serious Disease in Hebei Province, Hebei Medical Universitygrid.256883.2, Shijiazhuang, China.

J Virol ; 96(22): e0130922, 2022 11 23.

Article in En | MEDLINE | ID: mdl-36317881

Subject(s)

Receptors, CCR1; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human; Virus Replication; Humans; Chemokines; Receptors, CCR1/genetics; Receptors, CCR1/metabolism; Respiratory Syncytial Virus, Human/physiology; GTP-Binding Protein alpha Subunits/genetics; GTP-Binding Protein alpha Subunits/metabolism

Key words

CCL5; CCR1; HSP90; RSV; respiratory epithelial cell; respiratory syncytial virus

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Virus Replication / Respiratory Syncytial Virus, Human / Respiratory Syncytial Virus Infections / Receptors, CCR1 Limits: Humans Language: En Journal: J Virol Year: 2022 Type: Article Affiliation country: China

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