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Genetic deletion and pharmacologic inhibition of E3 ubiquitin ligase HOIP impairs the propagation of myeloid leukemia.
Jimbo, Koji; Hattori, Ayuna; Koide, Shuhei; Ito, Takahiro; Sasaki, Katsuhiro; Iwai, Kazuhiro; Nannya, Yasuhito; Iwama, Atsushi; Tojo, Arinobu; Konuma, Takaaki.
Affiliation
  • Jimbo K; Division of Hematopoietic Disease Control, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  • Hattori A; Division of Stem Cell and Molecular Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  • Koide S; Division of Molecular Therapy, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  • Ito T; Laboratory of Cell Fate Dynamics and Therapeutics, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan.
  • Sasaki K; Division of Stem Cell and Molecular Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  • Iwai K; Laboratory of Cell Fate Dynamics and Therapeutics, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan.
  • Nannya Y; Department of Molecular and Cellular Physiology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Iwama A; Department of Molecular and Cellular Physiology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Tojo A; Division of Hematopoietic Disease Control, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  • Konuma T; Department of Hematology/Oncology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Leukemia ; 37(1): 122-133, 2023 01.
Article in En | MEDLINE | ID: mdl-36352193
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid / Ubiquitin-Protein Ligases Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2023 Type: Article Affiliation country: Japan
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid / Ubiquitin-Protein Ligases Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2023 Type: Article Affiliation country: Japan