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Molecular glue CELMoD compounds are regulators of cereblon conformation.
Watson, Edmond R; Novick, Scott; Matyskiela, Mary E; Chamberlain, Philip P; H de la Peña, Andres; Zhu, Jinyi; Tran, Eileen; Griffin, Patrick R; Wertz, Ingrid E; Lander, Gabriel C.
Affiliation
  • Watson ER; Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, CA 92037, USA.
  • Novick S; Department of Molecular Medicine, Scripps Research, Jupiter, FL 33458, USA.
  • Matyskiela ME; UF Scripps Biomedical Research, University of Florida, Jupiter, FL 33458, USA.
  • Chamberlain PP; Bristol-Myers Squibb, San Diego, CA 92121, USA.
  • H de la Peña A; Bristol-Myers Squibb, San Diego, CA 92121, USA.
  • Zhu J; Bristol-Myers Squibb, San Diego, CA 92121, USA.
  • Tran E; Bristol-Myers Squibb, San Diego, CA 92121, USA.
  • Griffin PR; Bristol-Myers Squibb, San Diego, CA 92121, USA.
  • Wertz IE; Department of Molecular Medicine, Scripps Research, Jupiter, FL 33458, USA.
  • Lander GC; UF Scripps Biomedical Research, University of Florida, Jupiter, FL 33458, USA.
Science ; 378(6619): 549-553, 2022 11 04.
Article in En | MEDLINE | ID: mdl-36378961
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ubiquitin-Protein Ligases / Adaptor Proteins, Signal Transducing Language: En Journal: Science Year: 2022 Type: Article Affiliation country: United States
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ubiquitin-Protein Ligases / Adaptor Proteins, Signal Transducing Language: En Journal: Science Year: 2022 Type: Article Affiliation country: United States