Incidental diagnosis of bladder cancer in a national observational study in spain.
Actas Urol Esp (Engl Ed)
; 47(5): 296-302, 2023 06.
Article
in En, Es
| MEDLINE
| ID: mdl-36443223
ABSTRACT
INTRODUCTION:
Bladder cancer (BC) is a common malignancy in Spain. The aims of this study were to identify the proportion of patients diagnosed with BC incidentally or after symptomatic presentation in a contemporary period in Spain; to compare demographic, clinical, and pathologic characteristics between these groups.METHODS:
This was a retrospective analysis of a multi-centre observational study of 26 hospitals in the Spanish National Health System of all BCs newly diagnosed in 2011. The study represented 21.5% of the Spanish population and hospitals were selected in proportion to Spain's regions to ensure a representative sample. Patients were categorized by whether the cancer was diagnosed incidentally or after symptomatic presentation and baseline demographic, pathologic, and clinical characteristics were analyzed.RESULTS:
2472 were newly diagnosed with BC at the 26 participating Spanish hospitals with 308 (12.5%) of cases diagnosed incidentally and 2164 (87.5%) diagnosed after symptomatic presentation. No differences were observed between patients diagnosed incidentally vs. symptomatically in terms of demographics or measured co-morbidities. Compared to symptomatically diagnosed bladder tumours, those diagnosed incidentally were more likely to have a papillary appearance, to be significantly smaller, and less likely to have positive/suspicious cytology. Additionally, incidentally diagnosed bladder tumours were less likely to be muscle-invasive (11.7% vs. 25.0%, pâ¯<â¯0.01) nor aggressive at pathology, with 33.6% Grade 3 compared to 50.1%, (pâ¯<â¯0.01).CONCLUSIONS:
We identified a significant percentage (12.5%) of new bladder cancer diagnosis made incidentally in a representative sample of the Spanish population. These tumours exhibited less aggressive pathologic characteristics than their symptomatic counterparts.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Urinary Bladder Neoplasms
Type of study:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
Limits:
Humans
Country/Region as subject:
Europa
Language:
En
/
Es
Journal:
Actas Urol Esp (Engl Ed)
Year:
2023
Type:
Article