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Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding.
Rodarte, Justas V; Baehr, Carly; Hicks, Dustin; Liban, Tyler L; Weidle, Connor; Rupert, Peter B; Jahan, Rajwana; Wall, Abigail; McGuire, Andrew T; Strong, Roland K; Runyon, Scott; Pravetoni, Marco; Pancera, Marie.
Affiliation
  • Rodarte JV; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.
  • Baehr C; Department of Pharmacology, University of Minnesota Medical School, Minneapolis, MN, USA.
  • Hicks D; Department of Pharmacology, University of Minnesota Medical School, Minneapolis, MN, USA.
  • Liban TL; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.
  • Weidle C; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.
  • Rupert PB; Basic Science Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.
  • Jahan R; Research Triangle Institute International, Research Triangle Park, Durham, NC, USA.
  • Wall A; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.
  • McGuire AT; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA; Department of Global Health, University of Washington, Seattle, WA, USA; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.
  • Strong RK; Basic Science Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.
  • Runyon S; Research Triangle Institute International, Research Triangle Park, Durham, NC, USA.
  • Pravetoni M; Department of Pharmacology, University of Minnesota Medical School, Minneapolis, MN, USA; Department of Psychiatry and Behavioral Sciences, Department of Pharmacology, School of Medicine, University of Washington, Seattle, WA, USA; Center for Medication Development for Substance Use Disorders and Ov
  • Pancera M; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA. Electronic address: mpancera@fredhutch.org.
Structure ; 31(1): 20-32.e5, 2023 01 05.
Article in En | MEDLINE | ID: mdl-36513069
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Analgesics, Opioid / Nicotine Limits: Animals Language: En Journal: Structure Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA / BIOTECNOLOGIA Year: 2023 Type: Article Affiliation country: United States
Fulltext
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XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Analgesics, Opioid / Nicotine Limits: Animals Language: En Journal: Structure Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA / BIOTECNOLOGIA Year: 2023 Type: Article Affiliation country: United States