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Alternative splicing liberates a cryptic cytoplasmic isoform of mitochondrial MECR that antagonizes influenza virus.
Baker, Steven F; Meistermann, Helene; Tzouros, Manuel; Baker, Aaron; Golling, Sabrina; Polster, Juliane Siebourg; Ledwith, Mitchell P; Gitter, Anthony; Augustin, Angelique; Javanbakht, Hassan; Mehle, Andrew.
Affiliation
  • Baker SF; Department of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
  • Meistermann H; Roche Pharma Research and Early Development, Pharmaceutical Sciences-Biomarkers, Bioinformatics and Omics & Pathology, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Tzouros M; Roche Pharma Research and Early Development, Pharmaceutical Sciences-Biomarkers, Bioinformatics and Omics & Pathology, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Baker A; Department of Computer Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
  • Golling S; Morgridge Institute for Research, Madison, Wisconsin, United States of America.
  • Polster JS; Roche Pharma Research and Early Development, Pharmaceutical Sciences-Biomarkers, Bioinformatics and Omics & Pathology, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Ledwith MP; Roche Pharma Research and Early Development, Pharmaceutical Sciences-Biomarkers, Bioinformatics and Omics & Pathology, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Gitter A; Department of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
  • Augustin A; Department of Computer Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
  • Javanbakht H; Morgridge Institute for Research, Madison, Wisconsin, United States of America.
  • Mehle A; Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
PLoS Biol ; 20(12): e3001934, 2022 12.
Article in En | MEDLINE | ID: mdl-36542656

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Influenza A virus / Fatty Acid Desaturases Limits: Humans Language: En Journal: PLoS Biol Journal subject: BIOLOGIA Year: 2022 Type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Influenza A virus / Fatty Acid Desaturases Limits: Humans Language: En Journal: PLoS Biol Journal subject: BIOLOGIA Year: 2022 Type: Article Affiliation country: United States