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Extra-viral DNA in adeno-associated viral vector preparations induces TLR9-dependent innate immune responses in human plasmacytoid dendritic cells.
Bucher, Kirsten; Rodríguez-Bocanegra, Eduardo; Wissinger, Bernd; Strasser, Torsten; Clark, Simon J; Birkenfeld, Andreas L; Siegel-Axel, Dorothea; Fischer, M Dominik.
Affiliation
  • Bucher K; University Eye Hospital, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany. kirsten.bucher@med.uni-tuebingen.de.
  • Rodríguez-Bocanegra E; Institute for Ophthalmic Research, Centre for Ophthalmology, University Hospital Tübingen, University of Tübingen, Elfriede-Aulhorn-Strasse 7, 72076, Tübingen, Germany. kirsten.bucher@med.uni-tuebingen.de.
  • Wissinger B; University Eye Hospital, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.
  • Strasser T; Institute for Ophthalmic Research, Centre for Ophthalmology, University Hospital Tübingen, University of Tübingen, Elfriede-Aulhorn-Strasse 7, 72076, Tübingen, Germany.
  • Clark SJ; Institute for Ophthalmic Research, Centre for Ophthalmology, University Hospital Tübingen, University of Tübingen, Elfriede-Aulhorn-Strasse 7, 72076, Tübingen, Germany.
  • Birkenfeld AL; University Eye Hospital, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.
  • Siegel-Axel D; Institute for Ophthalmic Research, Centre for Ophthalmology, University Hospital Tübingen, University of Tübingen, Elfriede-Aulhorn-Strasse 7, 72076, Tübingen, Germany.
  • Fischer MD; University Eye Hospital, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.
Sci Rep ; 13(1): 1890, 2023 02 02.
Article in En | MEDLINE | ID: mdl-36732401
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA, Viral / Cytomegalovirus Infections Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Sci Rep Year: 2023 Type: Article Affiliation country: Germany
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA, Viral / Cytomegalovirus Infections Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Sci Rep Year: 2023 Type: Article Affiliation country: Germany