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Slower Calcium Handling Balances Faster Cross-Bridge Cycling in Human MYBPC3 HCM.
Pioner, Josè Manuel; Vitale, Giulia; Steczina, Sonette; Langione, Marianna; Margara, Francesca; Santini, Lorenzo; Giardini, Francesco; Lazzeri, Erica; Piroddi, Nicoletta; Scellini, Beatrice; Palandri, Chiara; Schuldt, Maike; Spinelli, Valentina; Girolami, Francesca; Mazzarotto, Francesco; van der Velden, Jolanda; Cerbai, Elisabetta; Tesi, Chiara; Olivotto, Iacopo; Bueno-Orovio, Alfonso; Sacconi, Leonardo; Coppini, Raffaele; Ferrantini, Cecilia; Regnier, Michael; Poggesi, Corrado.
Affiliation
  • Pioner JM; Department of Clinical and Experimental Medicine, Division of Physiology (J.M.P., G.V., M.L., N.P., B.S., C.T., C.F., C. Poggesi), University of Florence, Italy.
  • Vitale G; Department of Biology (J.M.P.), University of Florence, Italy.
  • Steczina S; Department of Clinical and Experimental Medicine, Division of Physiology (J.M.P., G.V., M.L., N.P., B.S., C.T., C.F., C. Poggesi), University of Florence, Italy.
  • Langione M; Department of Bioengineering, University of Washington, Seattle, WA (S.S., M.R.).
  • Margara F; Department of Clinical and Experimental Medicine, Division of Physiology (J.M.P., G.V., M.L., N.P., B.S., C.T., C.F., C. Poggesi), University of Florence, Italy.
  • Santini L; Department of Computer Science, University of Oxford, United Kingdom (F. Margara, A.B.-O.).
  • Giardini F; Department of NeuroFarBa (L. Santini, C. Palandri, V. Spinelli, E. Cerbai, R. Coppini), University of Florence, Italy.
  • Lazzeri E; European Laboratory for Non-Linear Spectroscopy (LENS) (F. Giardini, E. Lazzeri, C.F., C.P., E. Cerbai), University of Florence, Italy.
  • Piroddi N; European Laboratory for Non-Linear Spectroscopy (LENS) (F. Giardini, E. Lazzeri, C.F., C.P., E. Cerbai), University of Florence, Italy.
  • Scellini B; Department of Clinical and Experimental Medicine, Division of Physiology (J.M.P., G.V., M.L., N.P., B.S., C.T., C.F., C. Poggesi), University of Florence, Italy.
  • Palandri C; Department of Clinical and Experimental Medicine, Division of Physiology (J.M.P., G.V., M.L., N.P., B.S., C.T., C.F., C. Poggesi), University of Florence, Italy.
  • Schuldt M; Department of NeuroFarBa (L. Santini, C. Palandri, V. Spinelli, E. Cerbai, R. Coppini), University of Florence, Italy.
  • Spinelli V; Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Physiology, The Netherlands (M.S., J.v.d.V.).
  • Girolami F; Department of NeuroFarBa (L. Santini, C. Palandri, V. Spinelli, E. Cerbai, R. Coppini), University of Florence, Italy.
  • Mazzarotto F; Pediatric Cardiology (F. Girolami), IRCCS Meyer Children's Hospital, Florence, Italy.
  • van der Velden J; Department of Molecular and Translational Medicine, University of Brescia, Italy (F. Mazzarotto).
  • Cerbai E; National Heart and Lung Institute, Imperial College London, London, United Kingdom (F. Mazzarotto).
  • Tesi C; Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Physiology, The Netherlands (M.S., J.v.d.V.).
  • Olivotto I; Department of NeuroFarBa (L. Santini, C. Palandri, V. Spinelli, E. Cerbai, R. Coppini), University of Florence, Italy.
  • Bueno-Orovio A; European Laboratory for Non-Linear Spectroscopy (LENS) (F. Giardini, E. Lazzeri, C.F., C.P., E. Cerbai), University of Florence, Italy.
  • Sacconi L; Department of Clinical and Experimental Medicine, Division of Physiology (J.M.P., G.V., M.L., N.P., B.S., C.T., C.F., C. Poggesi), University of Florence, Italy.
  • Coppini R; Cardiogenetics Unit (I.O.), IRCCS Meyer Children's Hospital, Florence, Italy.
  • Ferrantini C; Referral Center for Cardiomyopathies, Careggi University Hospital, Florence, Italy (I.O.).
  • Regnier M; Department of Computer Science, University of Oxford, United Kingdom (F. Margara, A.B.-O.).
  • Poggesi C; Institute of Clinical Physiology (IFC), National Research Council, Florence, Italy (L. Sacconi).
Circ Res ; 132(5): 628-644, 2023 03 03.
Article in En | MEDLINE | ID: mdl-36744470
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cardiomyopathy, Hypertrophic / Induced Pluripotent Stem Cells Limits: Humans Language: En Journal: Circ Res Year: 2023 Type: Article Affiliation country: Italy
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cardiomyopathy, Hypertrophic / Induced Pluripotent Stem Cells Limits: Humans Language: En Journal: Circ Res Year: 2023 Type: Article Affiliation country: Italy