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GSK2795039 prevents RIP1-RIP3-MLKL-mediated cardiomyocyte necroptosis in doxorubicin-induced heart failure through inhibition of NADPH oxidase-derived oxidative stress.
Zhang, Xiao-Juan; Li, Lu; Wang, Ai-Ling; Guo, Hong-Xia; Zhao, Hui-Ping; Chi, Rui-Fang; Xu, Hui-Yu; Yang, Li-Guo; Li, Bao; Qin, Fu-Zhong; Wang, Jia-Pu.
Affiliation
  • Zhang XJ; The Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, PR China; Shanxi Medical University, Taiyuan 030001, Shanxi, PR China; Shanxi Province Cardiovascular Hospital, Taiyuan 030024, Shanxi, PR China.
  • Li L; Shanxi Medical University, Taiyuan 030001, Shanxi, PR China.
  • Wang AL; The Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, PR China; Shanxi Medical University, Taiyuan 030001, Shanxi, PR China.
  • Guo HX; The Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, PR China; Shanxi Medical University, Taiyuan 030001, Shanxi, PR China.
  • Zhao HP; The Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, PR China; Shanxi Medical University, Taiyuan 030001, Shanxi, PR China.
  • Chi RF; The Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, PR China; Shanxi Medical University, Taiyuan 030001, Shanxi, PR China.
  • Xu HY; Shanxi Medical University, Taiyuan 030001, Shanxi, PR China; Shanxi Province Cardiovascular Hospital, Taiyuan 030024, Shanxi, PR China.
  • Yang LG; The Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, PR China; Shanxi Medical University, Taiyuan 030001, Shanxi, PR China.
  • Li B; The Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, PR China; Shanxi Medical University, Taiyuan 030001, Shanxi, PR China. Electronic address: sxcvh13@sina.com.
  • Qin FZ; The Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, PR China; Shanxi Medical University, Taiyuan 030001, Shanxi, PR China. Electronic address: sxcvh13@sina.com.
  • Wang JP; Shanxi Province Cardiovascular Hospital, Taiyuan 030024, Shanxi, PR China.
Toxicol Appl Pharmacol ; 463: 116412, 2023 03 15.
Article in En | MEDLINE | ID: mdl-36764612
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Myocytes, Cardiac / Heart Failure Limits: Animals Language: En Journal: Toxicol Appl Pharmacol Year: 2023 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Myocytes, Cardiac / Heart Failure Limits: Animals Language: En Journal: Toxicol Appl Pharmacol Year: 2023 Type: Article