From 2D to 3D: Development of Monolayer Dopaminergic Neuronal and Midbrain Organoid Cultures for Parkinson's Disease Modeling and Regenerative Therapy.

Yeap, Yee Jie; Teddy, Tng J W; Lee, Mok Jung; Goh, Micaela; Lim, Kah Leong

Yeap, Yee Jie; Teddy, Tng J W; Lee, Mok Jung; Goh, Micaela; Lim, Kah Leong.

Affiliation

Yeap YJ; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 308232, Singapore.
Teddy TJW; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 308232, Singapore.
Lee MJ; Interdisciplinary Graduate Programme (IGP-Neuroscience), Nanyang Technological University, Singapore 639798, Singapore.
Goh M; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 308232, Singapore.
Lim KL; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 308232, Singapore.

Int J Mol Sci ; 24(3)2023 Jan 28.

Article in En | MEDLINE | ID: mdl-36768843

Subject(s)

Induced Pluripotent Stem Cells; Parkinson Disease; Pluripotent Stem Cells; Humans; Parkinson Disease/therapy; Mesencephalon; Dopaminergic Neurons; Organoids

Key words

Parkinson's Disease; allogeneic transplantation; clinical trial; dopaminergic neurons; mesencephalon; microfluidic; midbrain; organoids; pluripotent stem cells; regenerative medicine

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / Pluripotent Stem Cells / Induced Pluripotent Stem Cells Type of study: Guideline / Prognostic_studies Limits: Humans Language: En Journal: Int J Mol Sci Year: 2023 Type: Article Affiliation country: Singapore

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