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Phenyl Dihydrouracil: An Alternative Cereblon Binder for PROTAC Design.
Jarusiewicz, Jamie A; Yoshimura, Satoshi; Mayasundari, Anand; Actis, Marisa; Aggarwal, Anup; McGowan, Kevin; Yang, Lei; Li, Yong; Fu, Xiang; Mishra, Vibhor; Heath, Richard; Narina, Shilpa; Pruett-Miller, Shondra M; Nishiguchi, Gisele; Yang, Jun J; Rankovic, Zoran.
Affiliation
  • Jarusiewicz JA; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
  • Yoshimura S; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
  • Mayasundari A; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
  • Actis M; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
  • Aggarwal A; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
  • McGowan K; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
  • Yang L; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
  • Li Y; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
  • Fu X; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
  • Mishra V; Protein Production Facility, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
  • Heath R; Protein Production Facility, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
  • Narina S; Center for Advanced Genome Engineering, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
  • Pruett-Miller SM; Center for Advanced Genome Engineering, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
  • Nishiguchi G; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
  • Yang JJ; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
  • Rankovic Z; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
ACS Med Chem Lett ; 14(2): 141-145, 2023 Feb 09.
Article in En | MEDLINE | ID: mdl-36793425
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: ACS Med Chem Lett Year: 2023 Type: Article Affiliation country: United States
Fulltext
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XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: ACS Med Chem Lett Year: 2023 Type: Article Affiliation country: United States