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Changes in Body Mass Index with Longer-term Integrase Inhibitor Use: A Longitudinal Analysis of Data from the Randomized Trial to Prevent Vascular Events in Human Immunodeficiency Virus (REPRIEVE).
Kileel, Emma M; Malvestutto, Carlos D; Lo, Janet; Fitch, Kathleen V; Fichtenbaum, Carl J; Aberg, Judith A; Zanni, Markella V; Martinez, Esteban; Okeke, Nwora Lance; Kumar, Princy; Joao, Esau; Bares, Sara H; Berrner, Daniel; Smieja, Marek; Roa, Jhoanna C; McCallum, Sara; Douglas, Pamela S; Ribaudo, Heather J; Grinspoon, Steven K.
Affiliation
  • Kileel EM; Metabolism Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
  • Malvestutto CD; Division of Infectious Diseases, Ohio State University Medical Center, Columbus, Ohio, USA.
  • Lo J; Metabolism Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
  • Fitch KV; Metabolism Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
  • Fichtenbaum CJ; Division of Infectious Diseases, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
  • Aberg JA; Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Zanni MV; Metabolism Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
  • Martinez E; Infectious Diseases Service, Hospital Clinic and University of Barcelona, Barcelona, Spain.
  • Okeke NL; Department of Population Health Sciences, Duke University School of Medicine, Durham, North Carolina, USA.
  • Kumar P; Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
  • Joao E; Division of Infectious Diseases and Travel Medicine, Georgetown University School of Medicine, Washington, DC, USA.
  • Bares SH; Infectious Diseases Department, Hospital Federal dos Servidores do Estado, Rio de Janeiro, Brazil.
  • Berrner D; Division of Infectious Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA.
  • Smieja M; University of California-San Francisco at Zuckerberg San Francisco General Hospital, San Francisco, California, USA.
  • Roa JC; Division of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
  • McCallum S; DLH Corporation, Silver Spring, Maryland, USA.
  • Douglas PS; Metabolism Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
  • Ribaudo HJ; Duke University Research Institute, Duke University School of Medicine, Durham, North Carolina, USA.
  • Grinspoon SK; Center for Biostatistics in AIDS Research, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Clin Infect Dis ; 76(11): 2010-2013, 2023 06 08.
Article in En | MEDLINE | ID: mdl-36825498
ABSTRACT
Over 2-years of follow-up, integrase strand transfer inhibitor (INSTI)-use was associated with weight gain among those on an INSTI <2 years at entry (+0.27 kg/m2/year; 95% confidence interval [CI], .22 to .33 vs +0.17 kg/m2/year; 95% CI, .12 to .23; P = .01), but not those on an entry INSTI >2 years.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / HIV-1 / HIV Integrase Inhibitors / HIV Integrase Type of study: Clinical_trials / Risk_factors_studies Limits: Humans Language: En Journal: Clin Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2023 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / HIV-1 / HIV Integrase Inhibitors / HIV Integrase Type of study: Clinical_trials / Risk_factors_studies Limits: Humans Language: En Journal: Clin Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2023 Type: Article Affiliation country: United States