Bioexcitons by Design: How Do We Get There?
J Phys Chem B
; 127(9): 1872-1879, 2023 03 09.
Article
in En
| MEDLINE
| ID: mdl-36854126
ABSTRACT
Biological pigment-protein complexes (PPCs) exhibit a remarkable ability to tune the optical properties of biological excitons (bioexcitons) through specific pigment-protein interactions. While such fine-tuning allows natural systems (e.g., photosynthetic proteins) to carry out their native functions with near-optimal performance, native function itself is often suboptimal for applications such as biofuel production or quantum technology development. This perspective offers a look at near-term prospects for the rational reoptimization of PPC bioexcitons for new functions using site-directed mutagenesis. The primary focus is on the "structure-spectrum" challenge of understanding the relationships between structural features and spectroscopic properties. While recent examples demonstrate that site-directed mutagenesis can be used to tune nearly all key bioexciton parameters (e.g., site energies, interpigment couplings, and electronic-vibrational interactions), critical challenges remain before we achieve truly rational design of bioexciton properties.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Photosynthesis
/
Light-Harvesting Protein Complexes
Language:
En
Journal:
J Phys Chem B
Journal subject:
QUIMICA
Year:
2023
Type:
Article
Affiliation country:
United States