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A cell state specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma.
Banu, Matei A; Dovas, Athanassios; Argenziano, Michael G; Zhao, Wenting; Grajal, Henar Cuervo; Higgins, Dominique M O; Sperring, Colin P; Pereira, Brianna; Ye, Ling F; Mahajan, Aayushi; Humala, Nelson; Furnari, Julia L; Upadhyayula, Pavan S; Zandkarimi, Fereshteh; Nguyen, Trang T T; Wu, Peter B; Hai, Li; Karan, Charles; Razavilar, Aida; Siegelin, Markus D; Kitajewski, Jan; Bruce, Jeffrey N; Stockwell, Brent R; Sims, Peter A; Canoll, Peter D.
Affiliation
  • Banu MA; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA.
  • Dovas A; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.
  • Argenziano MG; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA.
  • Zhao W; Department of System Biology, Columbia University Irving Medical Center, New York, NY, USA.
  • Grajal HC; Spanish National Center for Cardiovascular Research, Madrid, Spain.
  • Higgins DMO; Department of Neurological Surgery, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
  • Sperring CP; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA.
  • Pereira B; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.
  • Ye LF; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.
  • Mahajan A; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA.
  • Humala N; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.
  • Furnari JL; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA.
  • Upadhyayula PS; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.
  • Zandkarimi F; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA.
  • Nguyen TTT; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.
  • Wu PB; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA.
  • Hai L; Department of Biological Sciences and Department of Chemistry, Columbia University, New York, NY, USA.
  • Karan C; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.
  • Razavilar A; Department of Neurological Surgery, UCLA Geffen School of Medicine, Los Angeles, CA, USA.
  • Siegelin MD; Sulzberger Columbia Genome Center, Columbia University, New York, NY, USA.
  • Kitajewski J; Sulzberger Columbia Genome Center, Columbia University, New York, NY, USA.
  • Bruce JN; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.
  • Stockwell BR; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.
  • Sims PA; University of Illinois Cancer Center, Department of Physiology and Biophysics, University of Illinois Chicago, Chicago, IL, USA.
  • Canoll PD; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, NY, USA.
bioRxiv ; 2023 Feb 23.
Article in En | MEDLINE | ID: mdl-36865302
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: BioRxiv Year: 2023 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: BioRxiv Year: 2023 Type: Article Affiliation country: United States