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Multiomics and machine-learning identify novel transcriptional and mutational signatures in amyotrophic lateral sclerosis.
Catanese, Alberto; Rajkumar, Sandeep; Sommer, Daniel; Masrori, Pegah; Hersmus, Nicole; Van Damme, Philip; Witzel, Simon; Ludolph, Albert; Ho, Ritchie; Boeckers, Tobias M; Mulaw, Medhanie.
Affiliation
  • Catanese A; Institute of Anatomy and Cell Biology, Ulm University School of Medicine, 89081 Ulm, Germany.
  • Rajkumar S; Translational Protein Biochemistry, German Center for Neurodegenerative Diseases (DZNE), Ulm site, 89081 Ulm, Germany.
  • Sommer D; Institute of Anatomy and Cell Biology, Ulm University School of Medicine, 89081 Ulm, Germany.
  • Masrori P; Institute of Anatomy and Cell Biology, Ulm University School of Medicine, 89081 Ulm, Germany.
  • Hersmus N; Laboratory of Neurobiology, Center for Brain & Disease Research, VIB, 3000 Leuven, Belgium.
  • Van Damme P; Department of Neurology, University Hospitals Leuven, 3000 Leuven, Belgium.
  • Witzel S; Experimental Neurology, Department of Neurosciences, Leuven Brain Institute, KU Leuven, 3000 Leuven, Belgium.
  • Ludolph A; Laboratory of Neurobiology, Center for Brain & Disease Research, VIB, 3000 Leuven, Belgium.
  • Ho R; Department of Neurology, University Hospitals Leuven, 3000 Leuven, Belgium.
  • Boeckers TM; Experimental Neurology, Department of Neurosciences, Leuven Brain Institute, KU Leuven, 3000 Leuven, Belgium.
  • Mulaw M; Laboratory of Neurobiology, Center for Brain & Disease Research, VIB, 3000 Leuven, Belgium.
Brain ; 146(9): 3770-3782, 2023 09 01.
Article in En | MEDLINE | ID: mdl-36883643
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neurodegenerative Diseases / Induced Pluripotent Stem Cells / Amyotrophic Lateral Sclerosis Type of study: Prognostic_studies Limits: Humans Language: En Journal: Brain Year: 2023 Type: Article Affiliation country: Germany
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neurodegenerative Diseases / Induced Pluripotent Stem Cells / Amyotrophic Lateral Sclerosis Type of study: Prognostic_studies Limits: Humans Language: En Journal: Brain Year: 2023 Type: Article Affiliation country: Germany