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AT-752 targets multiple sites and activities on the Dengue virus replication enzyme NS5.
Feracci, Mikael; Eydoux, Cécilia; Fattorini, Véronique; Lo Bello, Lea; Gauffre, Pierre; Selisko, Barbara; Sutto-Ortiz, Priscila; Shannon, Ashleigh; Xia, Hongjie; Shi, Pei-Yong; Noel, Mathieu; Debart, Françoise; Vasseur, Jean-Jacques; Good, Steve; Lin, Kai; Moussa, Adel; Sommadossi, Jean-Pierre; Chazot, Aurélie; Alvarez, Karine; Guillemot, Jean-Claude; Decroly, Etienne; Ferron, François; Canard, Bruno.
Affiliation
  • Feracci M; AFMB, CNRS, Aix-Marseille University, UMR 7257, Case 925, 163 Avenue de Luminy, 13288, Marseille Cedex 09, France.
  • Eydoux C; AFMB, CNRS, Aix-Marseille University, UMR 7257, Case 925, 163 Avenue de Luminy, 13288, Marseille Cedex 09, France.
  • Fattorini V; AFMB, CNRS, Aix-Marseille University, UMR 7257, Case 925, 163 Avenue de Luminy, 13288, Marseille Cedex 09, France.
  • Lo Bello L; AFMB, CNRS, Aix-Marseille University, UMR 7257, Case 925, 163 Avenue de Luminy, 13288, Marseille Cedex 09, France.
  • Gauffre P; AFMB, CNRS, Aix-Marseille University, UMR 7257, Case 925, 163 Avenue de Luminy, 13288, Marseille Cedex 09, France.
  • Selisko B; AFMB, CNRS, Aix-Marseille University, UMR 7257, Case 925, 163 Avenue de Luminy, 13288, Marseille Cedex 09, France.
  • Sutto-Ortiz P; AFMB, CNRS, Aix-Marseille University, UMR 7257, Case 925, 163 Avenue de Luminy, 13288, Marseille Cedex 09, France.
  • Shannon A; AFMB, CNRS, Aix-Marseille University, UMR 7257, Case 925, 163 Avenue de Luminy, 13288, Marseille Cedex 09, France.
  • Xia H; Department of Biochemistry and Molecular Biology, Sealy Institute for Drug Discovery, Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, Galveston, TX, USA.
  • Shi PY; Department of Biochemistry and Molecular Biology, Sealy Institute for Drug Discovery, Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, Galveston, TX, USA. Electronic address: peshi@utmb.edu.
  • Noel M; IBMM, UMR 5247 CNRS-UM1-UM2, Department of Nucleic Acids, Montpellier University, Place E. Bataillon, 34095, Montpellier Cedex 05, France.
  • Debart F; IBMM, UMR 5247 CNRS-UM1-UM2, Department of Nucleic Acids, Montpellier University, Place E. Bataillon, 34095, Montpellier Cedex 05, France.
  • Vasseur JJ; IBMM, UMR 5247 CNRS-UM1-UM2, Department of Nucleic Acids, Montpellier University, Place E. Bataillon, 34095, Montpellier Cedex 05, France.
  • Good S; Atea Pharmaceuticals, Inc., 225 Franklin St., Suite 2100, Boston, MA, 02110, USA.
  • Lin K; Atea Pharmaceuticals, Inc., 225 Franklin St., Suite 2100, Boston, MA, 02110, USA.
  • Moussa A; Atea Pharmaceuticals, Inc., 225 Franklin St., Suite 2100, Boston, MA, 02110, USA.
  • Sommadossi JP; Atea Pharmaceuticals, Inc., 225 Franklin St., Suite 2100, Boston, MA, 02110, USA.
  • Chazot A; AFMB, CNRS, Aix-Marseille University, UMR 7257, Case 925, 163 Avenue de Luminy, 13288, Marseille Cedex 09, France.
  • Alvarez K; AFMB, CNRS, Aix-Marseille University, UMR 7257, Case 925, 163 Avenue de Luminy, 13288, Marseille Cedex 09, France.
  • Guillemot JC; AFMB, CNRS, Aix-Marseille University, UMR 7257, Case 925, 163 Avenue de Luminy, 13288, Marseille Cedex 09, France.
  • Decroly E; AFMB, CNRS, Aix-Marseille University, UMR 7257, Case 925, 163 Avenue de Luminy, 13288, Marseille Cedex 09, France.
  • Ferron F; AFMB, CNRS, Aix-Marseille University, UMR 7257, Case 925, 163 Avenue de Luminy, 13288, Marseille Cedex 09, France.
  • Canard B; AFMB, CNRS, Aix-Marseille University, UMR 7257, Case 925, 163 Avenue de Luminy, 13288, Marseille Cedex 09, France. Electronic address: bruno.canard@univ-amu.fr.
Antiviral Res ; 212: 105574, 2023 04.
Article in En | MEDLINE | ID: mdl-36905944
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dengue / Dengue Virus Limits: Humans Language: En Journal: Antiviral Res Year: 2023 Type: Article Affiliation country: France
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dengue / Dengue Virus Limits: Humans Language: En Journal: Antiviral Res Year: 2023 Type: Article Affiliation country: France