Realistic scenarios of pesticide exposure alters multiple biomarkers in BOANA PULCHELLA (ANURA) Adult Frogs.
Ecotoxicology
; 32(3): 309-320, 2023 Apr.
Article
in En
| MEDLINE
| ID: mdl-36928692
ABSTRACT
Imazethapyr, a post-emergent herbicide used in worldwide soybean and corn crops, induces genetic and biochemical alterations in aquatic vertebrates. This study examined the relationship between biomarkers at different organization levels and imazethapyr real-life route exposure in Boana pulchella adults. Frogs were exposed to imazethapyr-based formulation Pivot® H (10.59%) at concentrations representing possible acute routes field runoff (S110 mg.L-1), exposure after direct foliar application (S2100 mg.L-1) and during direct foliar application (S31000 mg.L-1). Post-exposure, endpoints levels were evaluated organism alterations, biochemical activities and cytogenetic assays. Forty-eight hours post-exposure, antioxidant enzymes decrease, micronuclei induction and DNA damage were observed in all scenarios, while cholinesterase activity increase and body condition reduction were observed in frog-exposed to S3. Ninety-six hours post-exposure, frogs showed glutathione-S-transferase inhibition in S1, micronuclei induction in S2 and S3, and DNA-damage increase in S3. Herbicides routes of exposures in real-life could indicate that authorized applications have a risk to amphibian populations.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pesticides
/
Water Pollutants, Chemical
/
Herbicides
Limits:
Animals
Language:
En
Journal:
Ecotoxicology
Journal subject:
SAUDE AMBIENTAL
/
TOXICOLOGIA
Year:
2023
Type:
Article
Affiliation country:
Argentina