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Efficacy, safety, and tolerability of soticlestat as adjunctive therapy for the treatment of seizures in patients with Dup15q syndrome or CDKL5 deficiency disorder in an open-label signal-finding phase II study (ARCADE).
Demarest, Scott; Jeste, Shafali; Agarwal, Nitin; Arkilo, Dimitrios; Asgharnejad, Mahnaz; Hsiao, Samuel; Thibert, Ronald.
Affiliation
  • Demarest S; Department of Pediatrics and Neurology, University of Colorado School of Medicine, Children's Hospital Colorado, Aurora, Colorado, USA. Electronic address: Scott.Demarest@childrenscolorado.org.
  • Jeste S; Division of Neurology, Children's Hospital Los Angeles, Los Angeles, California, USA. Electronic address: sjeste@chla.usc.edu.
  • Agarwal N; Division of Pediatric Epilepsy, Minnesota Epilepsy Group, P.A., and Children's Minnesota, St Paul, Minnesota, USA. Electronic address: NAgarwal@mnepilepsy.net.
  • Arkilo D; Takeda Pharmaceutical Company Limited, Cambridge, Massachusetts, USA. Electronic address: arkdimi@hotmail.com.
  • Asgharnejad M; Takeda Pharmaceutical Company Limited, Cambridge, Massachusetts, USA. Electronic address: mahnaz.asgharnejad@takeda.com.
  • Hsiao S; Takeda Pharmaceutical Company Limited, Cambridge, Massachusetts, USA. Electronic address: sam.hsiao@takeda.com.
  • Thibert R; Massachusetts General Hospital for Children, Massachusetts General Hospital, Boston, Massachusetts, USA. Electronic address: RTHIBERT@mgh.harvard.edu.
Epilepsy Behav ; 142: 109173, 2023 05.
Article in En | MEDLINE | ID: mdl-37011526
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spasms, Infantile / Drug-Related Side Effects and Adverse Reactions Type of study: Clinical_trials / Diagnostic_studies Limits: Adult / Child / Humans / Infant Language: En Journal: Epilepsy Behav Journal subject: CIENCIAS DO COMPORTAMENTO / NEUROLOGIA Year: 2023 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spasms, Infantile / Drug-Related Side Effects and Adverse Reactions Type of study: Clinical_trials / Diagnostic_studies Limits: Adult / Child / Humans / Infant Language: En Journal: Epilepsy Behav Journal subject: CIENCIAS DO COMPORTAMENTO / NEUROLOGIA Year: 2023 Type: Article