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Antibody-guided proteases enable selective and catalytic degradation of challenging therapeutic targets.
Romei, Matthew G; Leonard, Brandon; Kim, Ingrid; Kim, Hok Seon; Lazar, Greg A.
Affiliation
  • Romei MG; Department of Antibody Engineering, Genentech Inc, South San Francisco, California, USA. Electronic address: mgromei92@gmail.com.
  • Leonard B; Department of Antibody Engineering, Genentech Inc, South San Francisco, California, USA.
  • Kim I; Department of Antibody Engineering, Genentech Inc, South San Francisco, California, USA.
  • Kim HS; Department of Antibody Engineering, Genentech Inc, South San Francisco, California, USA.
  • Lazar GA; Department of Antibody Engineering, Genentech Inc, South San Francisco, California, USA.
J Biol Chem ; 299(5): 104685, 2023 05.
Article in En | MEDLINE | ID: mdl-37031819
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Hydrolases / Endopeptidases / Biological Therapy / Antibodies, Monoclonal Language: En Journal: J Biol Chem Year: 2023 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Hydrolases / Endopeptidases / Biological Therapy / Antibodies, Monoclonal Language: En Journal: J Biol Chem Year: 2023 Type: Article