An ELISA-based assay for determining haemagglutinin potency in egg, cell, or recombinant protein derived influenza vaccines.

Bodle, Jesse; Vandenberg, Kirsten; Laurie, Karen; Barr, Ian G; Zhang, Ying; Rockman, Steven

Bodle, Jesse; Vandenberg, Kirsten; Laurie, Karen; Barr, Ian G; Zhang, Ying; Rockman, Steven.

Affiliation

Bodle J; Vaccine Product Development, CSL Seqirus Ltd, Parkville, VIC, Australia.
Vandenberg K; Vaccine Product Development, CSL Seqirus Ltd, Parkville, VIC, Australia.
Laurie K; Vaccine Product Development, CSL Seqirus Ltd, Parkville, VIC, Australia.
Barr IG; Collaborating Centre for Reference and Research on Influenza, World Health Organisation, Melbourne, VIC, Australia.
Zhang Y; Vaccine Product Development, CSL Seqirus Ltd, Holly Springs, NC, United States.
Rockman S; Vaccine Product Development, CSL Seqirus Ltd, Parkville, VIC, Australia.

Front Immunol ; 14: 1147028, 2023.

Article in En | MEDLINE | ID: mdl-37033922

Subject(s)

Cells; Eggs; Enzyme-Linked Immunosorbent Assay; Hemagglutinins; Influenza Vaccines; Recombinant Proteins; Animals; Humans; Antibodies, Monoclonal/chemistry; Antibodies, Monoclonal/immunology; Enzyme-Linked Immunosorbent Assay/methods; Hemagglutinin Glycoproteins, Influenza Virus; Hemagglutinins/chemistry; Immune Sera; Influenza Vaccines/chemistry; Influenza Vaccines/immunology; Influenza Vaccines/therapeutic use; Influenza, Human/prevention & control; Mammals; Recombinant Proteins/chemistry; Recombinant Proteins/metabolism; Cells/chemistry; Cells/immunology

Key words

ELISA - enzyme-linked immunosorbent assay; Monoclonal antibodies; immuno - assays; influenza potency assay; influenza vaccination; influenza vaccine antigen

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Recombinant Proteins / Enzyme-Linked Immunosorbent Assay / Influenza Vaccines / Cells / Eggs / Hemagglutinins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Front Immunol Year: 2023 Type: Article Affiliation country: Australia

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