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GRB2 promotes thymocyte positive selection by facilitating THEMIS-mediated inactivation of SHP1.
Choi, Seeyoung; Hatzihristidis, Teri; Gaud, Guillaume; Dutta, Avik; Lee, Jan; Arya, Awadhesh; Clubb, Lauren M; Stamos, Daniel B; Markovics, Adrienn; Mikecz, Katalin; Love, Paul.
Affiliation
  • Choi S; Section on Hematopoiesis and Lymphocyte Biology, Eunice Kennedy Shriver, National Institute of Child Health and Human Development, Bethesda, MD, USA.
  • Hatzihristidis T; Section on Hematopoiesis and Lymphocyte Biology, Eunice Kennedy Shriver, National Institute of Child Health and Human Development, Bethesda, MD, USA.
  • Gaud G; Section on Hematopoiesis and Lymphocyte Biology, Eunice Kennedy Shriver, National Institute of Child Health and Human Development, Bethesda, MD, USA.
  • Dutta A; Section on Hematopoiesis and Lymphocyte Biology, Eunice Kennedy Shriver, National Institute of Child Health and Human Development, Bethesda, MD, USA.
  • Lee J; Section on Hematopoiesis and Lymphocyte Biology, Eunice Kennedy Shriver, National Institute of Child Health and Human Development, Bethesda, MD, USA.
  • Arya A; Section on Hematopoiesis and Lymphocyte Biology, Eunice Kennedy Shriver, National Institute of Child Health and Human Development, Bethesda, MD, USA.
  • Clubb LM; Section on Hematopoiesis and Lymphocyte Biology, Eunice Kennedy Shriver, National Institute of Child Health and Human Development, Bethesda, MD, USA.
  • Stamos DB; Section on Hematopoiesis and Lymphocyte Biology, Eunice Kennedy Shriver, National Institute of Child Health and Human Development, Bethesda, MD, USA.
  • Markovics A; Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL, USA.
  • Mikecz K; Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL, USA.
  • Love P; Section on Hematopoiesis and Lymphocyte Biology, Eunice Kennedy Shriver, National Institute of Child Health and Human Development, Bethesda, MD, USA.
J Exp Med ; 220(7)2023 07 03.
Article in En | MEDLINE | ID: mdl-37067793
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Antigen, T-Cell / GRB2 Adaptor Protein / Protein Tyrosine Phosphatase, Non-Receptor Type 6 / Thymocytes Language: En Journal: J Exp Med Year: 2023 Type: Article Affiliation country: United States
Fulltext
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Antigen, T-Cell / GRB2 Adaptor Protein / Protein Tyrosine Phosphatase, Non-Receptor Type 6 / Thymocytes Language: En Journal: J Exp Med Year: 2023 Type: Article Affiliation country: United States