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Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease.
Duperron, Marie-Gabrielle; Knol, Maria J; Le Grand, Quentin; Evans, Tavia E; Mishra, Aniket; Tsuchida, Ami; Roshchupkin, Gennady; Konuma, Takahiro; Trégouët, David-Alexandre; Romero, Jose Rafael; Frenzel, Stefan; Luciano, Michelle; Hofer, Edith; Bourgey, Mathieu; Dueker, Nicole D; Delgado, Pilar; Hilal, Saima; Tankard, Rick M; Dubost, Florian; Shin, Jean; Saba, Yasaman; Armstrong, Nicola J; Bordes, Constance; Bastin, Mark E; Beiser, Alexa; Brodaty, Henry; Bülow, Robin; Carrera, Caty; Chen, Christopher; Cheng, Ching-Yu; Deary, Ian J; Gampawar, Piyush G; Himali, Jayandra J; Jiang, Jiyang; Kawaguchi, Takahisa; Li, Shuo; Macalli, Melissa; Marquis, Pascale; Morris, Zoe; Muñoz Maniega, Susana; Miyamoto, Susumu; Okawa, Masakazu; Paradise, Matthew; Parva, Pedram; Rundek, Tatjana; Sargurupremraj, Muralidharan; Schilling, Sabrina; Setoh, Kazuya; Soukarieh, Omar; Tabara, Yasuharu.
Affiliation
  • Duperron MG; Bordeaux Population Health Research Center, UMR 1219, University of Bordeaux, Inserm, Bordeaux, France.
  • Knol MJ; Department of Neurology, Institute of Neurodegenerative Diseases, Bordeaux University Hospital, Bordeaux, France.
  • Le Grand Q; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
  • Evans TE; Bordeaux Population Health Research Center, UMR 1219, University of Bordeaux, Inserm, Bordeaux, France.
  • Mishra A; Department of Clinical Genetics, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
  • Tsuchida A; Department of Radiology and Nuclear Medicine, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
  • Roshchupkin G; Bordeaux Population Health Research Center, UMR 1219, University of Bordeaux, Inserm, Bordeaux, France.
  • Konuma T; Bordeaux Population Health Research Center, UMR 1219, University of Bordeaux, Inserm, Bordeaux, France.
  • Trégouët DA; Groupe d'Imagerie Neurofonctionelle - Institut des maladies neurodégénératives (GIN-IMN), UMR 5293, University of Bordeaux, CNRS, CEA, Bordeaux, France.
  • Romero JR; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
  • Frenzel S; Department of Radiology and Nuclear Medicine, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
  • Luciano M; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.
  • Hofer E; Bordeaux Population Health Research Center, UMR 1219, University of Bordeaux, Inserm, Bordeaux, France.
  • Bourgey M; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.
  • Dueker ND; The Framingham Heart Study, Framingham, MA, USA.
  • Delgado P; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.
  • Hilal S; School of Psychology, University of Edinburgh, Edinburgh, UK.
  • Tankard RM; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria.
  • Dubost F; Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria.
  • Shin J; Department of Human Genetics, McGill University, Montreal, Quebec, Canada.
  • Saba Y; Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University, Montreal, Quebec, Canada.
  • Armstrong NJ; Canadian Centre for Computational Genomics, McGill University, Montreal, Quebec, Canada.
  • Bordes C; John P. Hussman Institute for Human Genomics, University of Miami, Miami, FL, USA.
  • Bastin ME; Institut de Recerca Vall d'hebron, Neurovascular Research Lab, Universitat Autònoma de Barcelona, Barcelona, Spain.
  • Beiser A; Hospital Universitari Vall d'Hebron, Neurology Department, Universitat Autònoma de Barcelona, Barcelona, Spain.
  • Brodaty H; Memory Aging and Cognition Center, National University Health System, Singapore, Singapore.
  • Bülow R; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Carrera C; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
  • Chen C; Department of Mathematics and Statistics, Curtin University, Perth, Western Australia, Australia.
  • Cheng CY; Department of Radiology and Nuclear Medicine, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
  • Deary IJ; Department of Medical Informatics, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
  • Gampawar PG; The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
  • Himali JJ; Departments of Physiology and Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada.
  • Jiang J; Bordeaux Population Health Research Center, UMR 1219, University of Bordeaux, Inserm, Bordeaux, France.
  • Kawaguchi T; Institute for Molecular Biology & Biochemistry, Gottfried Schatz Research Center (for Cell Signaling, Metabolism and Aging), Medical University of Graz, Graz, Austria.
  • Li S; Department of Mathematics and Statistics, Curtin University, Perth, Western Australia, Australia.
  • Macalli M; Bordeaux Population Health Research Center, UMR 1219, University of Bordeaux, Inserm, Bordeaux, France.
  • Marquis P; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
  • Morris Z; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.
  • Muñoz Maniega S; The Framingham Heart Study, Framingham, MA, USA.
  • Miyamoto S; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
  • Okawa M; Centre for Healthy Brain Ageing (CHeBA), Discipline of Psychiatry & Mental Health, University of New South Wales, Sydney, New South Wales, Australia.
  • Paradise M; Dementia Collaborative Research Centre Assessment and Better Care, UNSW, Sydney, New South Wales, Australia.
  • Parva P; Institute for Radiology and Neuroradiology, University Medicine Greifswald, Greifswald, Germany.
  • Rundek T; Stroke Pharmacogenomics and Genetics Group, Biomedical Research Institute Sant Pau (IIB Sant Pau), Barcelona, Spain.
  • Sargurupremraj M; Memory Aging and Cognition Center, National University Health System, Singapore, Singapore.
  • Schilling S; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Setoh K; Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Soukarieh O; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.
  • Tabara Y; Center for Innovation and Precision Eye Health, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Nat Med ; 29(4): 950-962, 2023 04.
Article in En | MEDLINE | ID: mdl-37069360
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stroke / Cerebral Small Vessel Diseases Type of study: Clinical_trials Limits: Humans Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2023 Type: Article Affiliation country: France
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stroke / Cerebral Small Vessel Diseases Type of study: Clinical_trials Limits: Humans Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2023 Type: Article Affiliation country: France