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Ligand and G-protein selectivity in the κ-opioid receptor.
Han, Jianming; Zhang, Jingying; Nazarova, Antonina L; Bernhard, Sarah M; Krumm, Brian E; Zhao, Lei; Lam, Jordy Homing; Rangari, Vipin A; Majumdar, Susruta; Nichols, David E; Katritch, Vsevolod; Yuan, Peng; Fay, Jonathan F; Che, Tao.
Affiliation
  • Han J; Department of Anesthesiology, Washington University in St Louis, St Louis, MO, USA.
  • Zhang J; Center for Clinical Pharmacology, University of Health Sciences and Pharmacy in St Louis and Washington University School of Medicine, St Louis, MO, USA.
  • Nazarova AL; Department of Cell Biology and Physiology, Washington University School of Medicine, St Louis, MO, USA.
  • Bernhard SM; Center for the Investigation of Membrane Excitability Diseases, Washington University School of Medicine, St Louis, MO, USA.
  • Krumm BE; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Zhao L; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Lam JH; Department of Quantitative and Computational Biology, University of Southern California, Los Angeles, CA, USA.
  • Rangari VA; Department of Chemistry, University of Southern California, Los Angeles, CA, USA.
  • Majumdar S; Center for New Technologies in Drug Discovery and Development, Bridge Institute, Michelson Center for Convergent Biosciences, University of Southern California, Los Angeles, CA, USA.
  • Nichols DE; Department of Anesthesiology, Washington University in St Louis, St Louis, MO, USA.
  • Katritch V; Center for Clinical Pharmacology, University of Health Sciences and Pharmacy in St Louis and Washington University School of Medicine, St Louis, MO, USA.
  • Yuan P; Department of Pharmacology, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
  • Fay JF; Department of Anesthesiology, Washington University in St Louis, St Louis, MO, USA.
  • Che T; Department of Quantitative and Computational Biology, University of Southern California, Los Angeles, CA, USA.
Nature ; 617(7960): 417-425, 2023 05.
Article in En | MEDLINE | ID: mdl-37138078
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Opioid, kappa / Cryoelectron Microscopy / Heterotrimeric GTP-Binding Proteins / Ligands Language: En Journal: Nature Year: 2023 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Opioid, kappa / Cryoelectron Microscopy / Heterotrimeric GTP-Binding Proteins / Ligands Language: En Journal: Nature Year: 2023 Type: Article Affiliation country: United States