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Recent Advances in Senolysis for Age-Related Diseases.
Aratani, Sae; Nakanishi, Makoto.
Affiliation
  • Aratani S; Division of Cancer Cell Biology, Institute of Medical Science, University of Tokyo, Tokyo, Japan.
  • Nakanishi M; Department of Endocrinology, Metabolism and Nephrology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan.
Physiology (Bethesda) ; 38(5): 0, 2023 09 01.
Article in En | MEDLINE | ID: mdl-37191645
ABSTRACT
Cellular senescence plays a central role in aging and geriatric diseases. Senolysis is a promising new strategy that selectively kills and eliminates senescent cells to control aging. To date, various senolytic drugs have been discovered and shown efficacy. This review highlights how we can benefit from senolysis.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aging / Cellular Senescence Limits: Aged / Humans Language: En Journal: Physiology (Bethesda) Journal subject: FISIOLOGIA Year: 2023 Type: Article Affiliation country: Japan
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aging / Cellular Senescence Limits: Aged / Humans Language: En Journal: Physiology (Bethesda) Journal subject: FISIOLOGIA Year: 2023 Type: Article Affiliation country: Japan