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UTX inactivation in germinal center B cells promotes the development of multiple myeloma with extramedullary disease.
Rizq, Ola; Mimura, Naoya; Oshima, Motohiko; Momose, Shuji; Takayama, Naoya; Itokawa, Naoki; Koide, Shuhei; Shibamiya, Asuka; Miyamoto-Nagai, Yurie; Rizk, Mohamed; Nakajima-Takagi, Yaeko; Aoyama, Kazumasa; Wang, Changshan; Saraya, Atsunori; Ito, Ryoji; Seimiya, Masanori; Watanabe, Mariko; Yamasaki, Satoshi; Shibata, Tatsuhiro; Yamaguchi, Kiyoshi; Furukawa, Yoichi; Chiba, Tetsuhiro; Sakaida, Emiko; Nakaseko, Chiaki; Tamaru, Jun-Ichi; Tai, Yu-Tzu; Anderson, Kenneth C; Honda, Hiroaki; Iwama, Atsushi.
Affiliation
  • Rizq O; Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  • Mimura N; Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Oshima M; Department of Hematology, Chiba University Hospital, Chiba, Japan.
  • Momose S; Jerome Lipper Multiple Myeloma Center, Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Takayama N; Department of Hematology, Chiba University Hospital, Chiba, Japan. naoyamimura@chiba-u.jp.
  • Itokawa N; Department of Transfusion Medicine and Cell Therapy, Chiba University Hospital, Chiba, Japan. naoyamimura@chiba-u.jp.
  • Koide S; Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  • Shibamiya A; Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Miyamoto-Nagai Y; Department of Pathology, Saitama Medical Center, Saitama Medical University, Kawagoe, Japan.
  • Rizk M; Department of Regenerative Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Nakajima-Takagi Y; Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  • Aoyama K; Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  • Wang C; Department of Hematology, Chiba University Hospital, Chiba, Japan.
  • Saraya A; Department of Hematology, Chiba University Hospital, Chiba, Japan.
  • Ito R; Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  • Seimiya M; Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Watanabe M; Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  • Yamasaki S; Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Shibata T; Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  • Yamaguchi K; Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Furukawa Y; Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Chiba T; The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, School of Life Sciences, Inner Mongolia University, Hohhot, China.
  • Sakaida E; Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Nakaseko C; Central Institute for Experimental Animals, Kanagawa, Japan.
  • Tamaru JI; Department of Medical Technology and Sciences, School of Health Sciences at Narita, International University of Health and Welfare, Narita, Japan.
  • Tai YT; Department of Clinical Laboratory, Chiba University Hospital, Chiba, Japan.
  • Anderson KC; Laboratory of Molecular Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  • Honda H; Laboratory of Molecular Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  • Iwama A; Division of Clinical Genome Research, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Leukemia ; 37(9): 1895-1907, 2023 09.
Article in En | MEDLINE | ID: mdl-37198323
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Multiple Myeloma Limits: Animals Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2023 Type: Article Affiliation country: Japan
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Multiple Myeloma Limits: Animals Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2023 Type: Article Affiliation country: Japan