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Lipid nanoparticles allow efficient and harmless ex vivo gene editing of human hematopoietic cells.
Vavassori, Valentina; Ferrari, Samuele; Beretta, Stefano; Asperti, Claudia; Albano, Luisa; Annoni, Andrea; Gaddoni, Chiara; Varesi, Angelica; Soldi, Monica; Cuomo, Alessandro; Bonaldi, Tiziana; Radrizzani, Marina; Merelli, Ivan; Naldini, Luigi.
Affiliation
  • Vavassori V; San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Ferrari S; San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Beretta S; Vita-Salute San Raffaele University, Milan, Italy.
  • Asperti C; San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Albano L; San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Annoni A; San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Gaddoni C; San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Varesi A; San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Soldi M; San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Cuomo A; San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Bonaldi T; Department of Molecular Oncology, IEO, European Institute of Oncology IRCCS, Milan, Italy.
  • Radrizzani M; Department of Molecular Oncology, IEO, European Institute of Oncology IRCCS, Milan, Italy.
  • Merelli I; Department of Oncology and Haematology-Oncology, University of Milan, Milan, Italy.
  • Naldini L; San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Blood ; 142(9): 812-826, 2023 08 31.
Article in En | MEDLINE | ID: mdl-37294917
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tumor Suppressor Protein p53 / Gene Editing Limits: Humans Language: En Journal: Blood Year: 2023 Type: Article Affiliation country: Italy
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tumor Suppressor Protein p53 / Gene Editing Limits: Humans Language: En Journal: Blood Year: 2023 Type: Article Affiliation country: Italy