Non-Nutritive Sweetened Beverages Impair Therapeutic Benefits of Metformin in Prediabetic Diet-Induced Obese Mice.

Singh, Arashdeep; Rourk, Katelyn; Bernier, Angelina; de Lartigue, Guillaume

Singh, Arashdeep; Rourk, Katelyn; Bernier, Angelina; de Lartigue, Guillaume.

Affiliation

Singh A; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, FL 32610, USA.
Rourk K; Monell Chemical Senses Center, Philadelphia, PA 19104, USA.
Bernier A; Department of Neuroscience, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19019, USA.
de Lartigue G; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, FL 32610, USA.

Nutrients ; 15(11)2023 May 25.

Article in En | MEDLINE | ID: mdl-37299435

Subject(s)

Diabetes Mellitus, Type 2; High Fructose Corn Syrup; Metformin; Non-Nutritive Sweeteners; Prediabetic State; Sugar-Sweetened Beverages; Animals; Mice; Diabetes Mellitus, Type 2/drug therapy; Diet, High-Fat/adverse effects; High Fructose Corn Syrup/adverse effects; Metformin/pharmacology; Metformin/therapeutic use; Mice, Obese; Non-Nutritive Sweeteners/adverse effects; Obesity/drug therapy; Obesity/etiology; Saccharin; Glucose Intolerance

Key words

artificial sweeteners; diabetes; high-fat diet; obesity; sugar

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prediabetic State / Diabetes Mellitus, Type 2 / Non-Nutritive Sweeteners / High Fructose Corn Syrup / Sugar-Sweetened Beverages / Metformin Type of study: Etiology_studies Limits: Animals Language: En Journal: Nutrients Year: 2023 Type: Article Affiliation country: United States

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