Varicella-zoster virus proteome-wide T-cell screening demonstrates low prevalence of virus-specific CD8 T-cells in latently infected human trigeminal ganglia.

van Gent, Michiel; Ouwendijk, Werner J D; Campbell, Victoria L; Laing, Kerry J; Verjans, Georges M G M; Koelle, David M

van Gent, Michiel; Ouwendijk, Werner J D; Campbell, Victoria L; Laing, Kerry J; Verjans, Georges M G M; Koelle, David M.

Affiliation

van Gent M; HerpesLabNL, Department of Viroscience, Erasmus Medical Center, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands.
Ouwendijk WJD; HerpesLabNL, Department of Viroscience, Erasmus Medical Center, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands.
Campbell VL; Department of Medicine, University of Washington, Seattle, WA, 98195, USA.
Laing KJ; Department of Medicine, University of Washington, Seattle, WA, 98195, USA.
Verjans GMGM; HerpesLabNL, Department of Viroscience, Erasmus Medical Center, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands. g.verjans@erasmusmc.nl.
Koelle DM; Department of Medicine, University of Washington, Seattle, WA, 98195, USA. dkoelle@medicine.washington.edu.

J Neuroinflammation ; 20(1): 141, 2023 Jun 12.

Article in En | MEDLINE | ID: mdl-37308917

Subject(s)

Herpesvirus 1, Human; Proteome; Adult; Humans; Herpesvirus 3, Human; Prevalence; Trigeminal Ganglion; CD8-Positive T-Lymphocytes; Epitopes

Key words

Herpes simplex virus; Human; Latency; T-cells; Trigeminal ganglion; Varicella-zoster virus

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Herpesvirus 1, Human / Proteome Type of study: Diagnostic_studies / Prevalence_studies / Risk_factors_studies / Screening_studies Limits: Adult / Humans Language: En Journal: J Neuroinflammation Journal subject: NEUROLOGIA Year: 2023 Type: Article Affiliation country: Netherlands

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