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Blockade of IL-11 Trans-Signaling or JAK2/STAT3 Signaling Ameliorates the Profibrotic Effect of IL-11.
Ye, Wenjing; Wang, Qian; Zhao, Li; Wang, Changcheng; Zhang, Dandan; Zhou, Mengyu; Chen, Fangfang; Wang, Weiguo; Zhu, Zaihua; Guo, Wenyu; Liu, Yun; Zou, Hejian; Xue, Yu.
Affiliation
  • Ye W; Department of Rheumatology, Huashan Hospital, Fudan University, Shanghai, China.
  • Wang Q; Department of Rheumatology, Huashan Hospital, Fudan University, Shanghai, China.
  • Zhao L; Department of Rheumatology, Huashan Hospital, Fudan University, Shanghai, China.
  • Wang C; Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
  • Zhang D; MOE Key Laboratory of Metabolism and Molecular Medicine, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
  • Zhou M; MOE Key Laboratory of Metabolism and Molecular Medicine, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
  • Chen F; Department of Rheumatology, Huashan Hospital, Fudan University, Shanghai, China.
  • Wang W; Department of Rheumatology, Huashan Hospital, Fudan University, Shanghai, China.
  • Zhu Z; Department of Rheumatology, Huashan Hospital, Fudan University, Shanghai, China.
  • Guo W; Clinical Development, I-Mab Biopharma, Hangzhou, China.
  • Liu Y; MOE Key Laboratory of Metabolism and Molecular Medicine, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
  • Zou H; Department of Rheumatology, Huashan Hospital, Fudan University, Shanghai, China.
  • Xue Y; Department of Rheumatology, Huashan Hospital, Fudan University, Shanghai, China.
Immunol Invest ; 52(6): 703-716, 2023 Nov.
Article in En | MEDLINE | ID: mdl-37401665
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Scleroderma, Systemic / Interleukin-11 Limits: Animals / Humans Language: En Journal: Immunol Invest Journal subject: ALERGIA E IMUNOLOGIA Year: 2023 Type: Article Affiliation country: China
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Scleroderma, Systemic / Interleukin-11 Limits: Animals / Humans Language: En Journal: Immunol Invest Journal subject: ALERGIA E IMUNOLOGIA Year: 2023 Type: Article Affiliation country: China