EEG functional connectivity after perinatal stroke.
Cereb Cortex
; 33(17): 9927-9935, 2023 08 23.
Article
in En
| MEDLINE
| ID: mdl-37415237
ABSTRACT
Impaired cognitive functioning after perinatal stroke has been associated with long-term functional brain network changes. We explored brain functional connectivity using a 64-channel resting-state electroencephalogram in 12 participants, aged 5-14 years with a history of unilateral perinatal arterial ischemic or haemorrhagic stroke. A control group of 16 neurologically healthy subjects was also included-each test subject was compared with multiple control subjects, matched by sex and age. Functional connectomes from the alpha frequency band were calculated for each subject and the differences in network graph metrics between the 2 groups were analyzed. Our results suggest that the functional brain networks of children with perinatal stroke show evidence of disruption even years after the insult and that the scale of changes appears to be influenced by the lesion volume. The networks remain more segregated and show a higher synchronization at both whole-brain and intrahemispheric level. Total interhemispheric strength was higher in children with perinatal stroke compared with healthy controls.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Stroke
/
Connectome
Limits:
Child
/
Humans
Language:
En
Journal:
Cereb Cortex
Journal subject:
CEREBRO
Year:
2023
Type:
Article
Affiliation country:
Slovenia