Instrumental variable model average with applications in Mendelian randomization.

Seng, Loraine Liping; Liu, Ching-Ti; Wang, Jingli; Li, Jialiang

Instrumental variable model average with applications in Mendelian randomization.

Seng, Loraine Liping; Liu, Ching-Ti; Wang, Jingli; Li, Jialiang.

Affiliation

Seng LL; Department of Statistics and Data Science, National University of Singapore, Singapore.
Liu CT; Duke-NUS Graduate Medical School, National University of Singapore, Singapore.
Wang J; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.
Li J; Department of Statistics, National Cheng Kung University, Tainan, Taiwan.

Stat Med ; 42(19): 3547-3567, 2023 08 30.

Article in En | MEDLINE | ID: mdl-37476915

Subject(s)

Genetic Variation; Mendelian Randomization Analysis; Humans; Mendelian Randomization Analysis/methods; Causality; Phenotype; Blood Pressure/genetics; Polymorphism, Single Nucleotide; Genome-Wide Association Study

Key words

causal inference; genetics; genome-wide association study; instrument variable; model average; penalty function; single nucleotide polymorphism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Variation / Mendelian Randomization Analysis Type of study: Clinical_trials / Observational_studies / Prognostic_studies Limits: Humans Language: En Journal: Stat Med Year: 2023 Type: Article Affiliation country: Singapore

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