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Conserved class B GPCR activation by a biased intracellular agonist.
Zhao, Li-Hua; He, Qian; Yuan, Qingning; Gu, Yimin; He, Xinheng; Shan, Hong; Li, Junrui; Wang, Kai; Li, Yang; Hu, Wen; Wu, Kai; Shen, Jianhua; Xu, H Eric.
Affiliation
  • Zhao LH; State Key Laboratory of Drug Research, Center for Structure and Function of Drug Targets, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. zhaolihuawendy@simm.ac.cn.
  • He Q; University of Chinese Academy of Sciences, Beijing, China. zhaolihuawendy@simm.ac.cn.
  • Yuan Q; State Key Laboratory of Drug Research, Center for Structure and Function of Drug Targets, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Gu Y; University of Chinese Academy of Sciences, Beijing, China.
  • He X; State Key Laboratory of Drug Research, Center for Structure and Function of Drug Targets, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Shan H; State Key Laboratory of Drug Research, Center for Structure and Function of Drug Targets, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Li J; University of Chinese Academy of Sciences, Beijing, China.
  • Wang K; State Key Laboratory of Drug Research, Center for Structure and Function of Drug Targets, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Li Y; University of Chinese Academy of Sciences, Beijing, China.
  • Hu W; State Key Laboratory of Drug Research, Center for Structure and Function of Drug Targets, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Wu K; State Key Laboratory of Drug Research, Center for Structure and Function of Drug Targets, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Shen J; State Key Laboratory of Drug Research, Center for Structure and Function of Drug Targets, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Xu HE; State Key Laboratory of Drug Research, Center for Structure and Function of Drug Targets, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Nature ; 621(7979): 635-641, 2023 Sep.
Article in En | MEDLINE | ID: mdl-37524305
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spiro Compounds / Receptors, G-Protein-Coupled / Imidazolidines Limits: Humans Language: En Journal: Nature Year: 2023 Type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spiro Compounds / Receptors, G-Protein-Coupled / Imidazolidines Limits: Humans Language: En Journal: Nature Year: 2023 Type: Article Affiliation country: China