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A semimechanistic pharmacokinetic/pharmacodynamic model for alanine aminotransferase-based hepatotoxicity of methotrexate in paediatric patients with acute lymphoid leukaemia.
Yin, Qiufen; Cheng, Zeneng; Yang, Minghua; Wang, Shengfeng; Xie, Feifan.
Affiliation
  • Yin Q; Division of Biopharmaceutics and Pharmacokinetics, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, China.
  • Cheng Z; Division of Biopharmaceutics and Pharmacokinetics, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, China.
  • Yang M; Postdoctoral Research Station of Clinical Medicine and Department of Paediatrics, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Wang S; Postdoctoral Research Station of Clinical Medicine and Department of Paediatrics, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Xie F; Department of Pharmacy, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Br J Clin Pharmacol ; 89(12): 3637-3647, 2023 12.
Article in En | MEDLINE | ID: mdl-37548052
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Precursor Cell Lymphoblastic Leukemia-Lymphoma / Chemical and Drug Induced Liver Injury Type of study: Observational_studies Limits: Child / Humans Language: En Journal: Br J Clin Pharmacol Year: 2023 Type: Article Affiliation country: China
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Precursor Cell Lymphoblastic Leukemia-Lymphoma / Chemical and Drug Induced Liver Injury Type of study: Observational_studies Limits: Child / Humans Language: En Journal: Br J Clin Pharmacol Year: 2023 Type: Article Affiliation country: China