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Targeting STING oligomerization with small-molecule inhibitors.
Humphries, Fiachra; Shmuel-Galia, Liraz; Jiang, Zhaozhao; Zhou, Jeffrey Y; Barasa, Leonard; Mondal, Santanu; Wilson, Ruth; Sultana, Nadia; Shaffer, Scott A; Ng, Sze-Ling; Pesiridis, G Scott; Thompson, Paul R; Fitzgerald, Katherine A.
Affiliation
  • Humphries F; Division of Innate Immunity, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA 01605.
  • Shmuel-Galia L; Division of Innate Immunity, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA 01605.
  • Jiang Z; Division of Innate Immunity, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA 01605.
  • Zhou JY; Division of Innate Immunity, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA 01605.
  • Barasa L; Program in Chemical Biology, Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA 01605.
  • Mondal S; Program in Chemical Biology, Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA 01605.
  • Wilson R; Kusuma School of Biological Sciences, Indian Institute of Technology Delhi, New Delhi 110016, India.
  • Sultana N; Division of Innate Immunity, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA 01605.
  • Shaffer SA; Program in Chemical Biology, Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA 01605.
  • Ng SL; Mass Spectrometry Facility, Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA 01545.
  • Pesiridis GS; Program in Chemical Biology, Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA 01605.
  • Thompson PR; Mass Spectrometry Facility, Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA 01545.
  • Fitzgerald KA; Immunology Research Unit, GlaxoSmithKline, Philadelphia, PA 19426.
Proc Natl Acad Sci U S A ; 120(33): e2305420120, 2023 08 15.
Article in En | MEDLINE | ID: mdl-37549268
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interferon Type I / Membrane Proteins Type of study: Prognostic_studies Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2023 Type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interferon Type I / Membrane Proteins Type of study: Prognostic_studies Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2023 Type: Article