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R-loop-dependent promoter-proximal termination ensures genome stability.
Xu, Congling; Li, Chengyu; Chen, Jiwei; Xiong, Yan; Qiao, Zhibin; Fan, Pengyu; Li, Conghui; Ma, Shuangyu; Liu, Jin; Song, Aixia; Tao, Bolin; Xu, Tao; Xu, Wei; Chi, Yayun; Xue, Jingyan; Wang, Pu; Ye, Dan; Gu, Hongzhou; Zhang, Peng; Wang, Qiong; Xiao, Ruijing; Cheng, Jingdong; Zheng, Hai; Yu, Xiaoli; Zhang, Zhen; Wu, Jiong; Liang, Kaiwei; Liu, Yan-Jun; Lu, Huasong; Chen, Fei Xavier.
Affiliation
  • Xu C; Fudan University Shanghai Cancer Center, Institutes of Biomedical Sciences, State Key Laboratory of Genetic Engineering, Shanghai Key Laboratory of Medical Epigenetics, Shanghai Key Laboratory of Radiation Oncology, Human Phenome Institute, Fudan University, Shanghai, China.
  • Li C; Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.
  • Chen J; Fudan University Shanghai Cancer Center, Institutes of Biomedical Sciences, State Key Laboratory of Genetic Engineering, Shanghai Key Laboratory of Medical Epigenetics, Shanghai Key Laboratory of Radiation Oncology, Human Phenome Institute, Fudan University, Shanghai, China.
  • Xiong Y; Fudan University Shanghai Cancer Center, Institutes of Biomedical Sciences, State Key Laboratory of Genetic Engineering, Shanghai Key Laboratory of Medical Epigenetics, Shanghai Key Laboratory of Radiation Oncology, Human Phenome Institute, Fudan University, Shanghai, China.
  • Qiao Z; Fudan University Shanghai Cancer Center, Institutes of Biomedical Sciences, State Key Laboratory of Genetic Engineering, Shanghai Key Laboratory of Medical Epigenetics, Shanghai Key Laboratory of Radiation Oncology, Human Phenome Institute, Fudan University, Shanghai, China.
  • Fan P; Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Fudan University, Shanghai, China.
  • Li C; Fudan University Shanghai Cancer Center, Institutes of Biomedical Sciences, State Key Laboratory of Genetic Engineering, Shanghai Key Laboratory of Medical Epigenetics, Shanghai Key Laboratory of Radiation Oncology, Human Phenome Institute, Fudan University, Shanghai, China.
  • Ma S; Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
  • Liu J; Department of Pathophysiology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
  • Song A; Department of Histoembryology, Genetics and Developmental Biology, Shanghai Key Laboratory of Reproductive Medicine, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Tao B; Fudan University Shanghai Cancer Center, Institutes of Biomedical Sciences, State Key Laboratory of Genetic Engineering, Shanghai Key Laboratory of Medical Epigenetics, Shanghai Key Laboratory of Radiation Oncology, Human Phenome Institute, Fudan University, Shanghai, China.
  • Xu T; Fudan University Shanghai Cancer Center, Institutes of Biomedical Sciences, State Key Laboratory of Genetic Engineering, Shanghai Key Laboratory of Medical Epigenetics, Shanghai Key Laboratory of Radiation Oncology, Human Phenome Institute, Fudan University, Shanghai, China.
  • Xu W; Fudan University Shanghai Cancer Center, Institutes of Biomedical Sciences, State Key Laboratory of Genetic Engineering, Shanghai Key Laboratory of Medical Epigenetics, Shanghai Key Laboratory of Radiation Oncology, Human Phenome Institute, Fudan University, Shanghai, China.
  • Chi Y; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, China.
  • Xue J; Department of Orthopedic Oncology, Changzheng Hospital, Second Military Medical University, Shanghai, China.
  • Wang P; Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.
  • Ye D; Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.
  • Gu H; Huashan Hospital, Fudan University, Shanghai Key Laboratory of Medical Epigenetics, Molecular and Cell Biology Lab, Institutes of Biomedical Sciences, Shanghai Medical College of Fudan University, Shanghai, China.
  • Zhang P; Huashan Hospital, Fudan University, Shanghai Key Laboratory of Medical Epigenetics, Molecular and Cell Biology Lab, Institutes of Biomedical Sciences, Shanghai Medical College of Fudan University, Shanghai, China.
  • Wang Q; Fudan University Shanghai Cancer Center, Institutes of Biomedical Sciences, State Key Laboratory of Genetic Engineering, Shanghai Key Laboratory of Medical Epigenetics, Shanghai Key Laboratory of Radiation Oncology, Human Phenome Institute, Fudan University, Shanghai, China.
  • Xiao R; Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
  • Cheng J; Department of Histoembryology, Genetics and Developmental Biology, Shanghai Key Laboratory of Reproductive Medicine, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Zheng H; Department of Pathophysiology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
  • Yu X; Fudan University Shanghai Cancer Center, Institutes of Biomedical Sciences, State Key Laboratory of Genetic Engineering, Shanghai Key Laboratory of Medical Epigenetics, Shanghai Key Laboratory of Radiation Oncology, Human Phenome Institute, Fudan University, Shanghai, China.
  • Zhang Z; Fudan University Shanghai Cancer Center, Institutes of Biomedical Sciences, State Key Laboratory of Genetic Engineering, Shanghai Key Laboratory of Medical Epigenetics, Shanghai Key Laboratory of Radiation Oncology, Human Phenome Institute, Fudan University, Shanghai, China.
  • Wu J; Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Fudan University, Shanghai, China.
  • Liang K; Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Fudan University, Shanghai, China.
  • Liu YJ; Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.
  • Lu H; Department of Pathophysiology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
  • Chen FX; Fudan University Shanghai Cancer Center, Institutes of Biomedical Sciences, State Key Laboratory of Genetic Engineering, Shanghai Key Laboratory of Medical Epigenetics, Shanghai Key Laboratory of Radiation Oncology, Human Phenome Institute, Fudan University, Shanghai, China.
Nature ; 621(7979): 610-619, 2023 Sep.
Article in En | MEDLINE | ID: mdl-37557913
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Promoter Regions, Genetic / Genomic Instability / Transcription Termination, Genetic / R-Loop Structures Limits: Humans Language: En Journal: Nature Year: 2023 Type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Promoter Regions, Genetic / Genomic Instability / Transcription Termination, Genetic / R-Loop Structures Limits: Humans Language: En Journal: Nature Year: 2023 Type: Article Affiliation country: China