Linking nanomaterial-induced mitochondrial dysfunction to existing adverse outcome pathways for chemicals.
ALTEX
; 41(1): 76-90, 2024 01 09.
Article
in En
| MEDLINE
| ID: mdl-37606097
This article investigates commonalities in the toxicity pathways of chemicals and nanomaterials. Nanomaterials have been found to affect the function of mitochondria, the powerhouses within every human cell. Mitochondrial dysfunction may cause harmful effects such as cellular damage and inflammation. By linking these findings to existing adverse outcome pathways for chemicals, the research provides valuable insights for assessing the risks associated with nanomaterial exposure. This work is crucial for understanding the potential health implications of nanomaterials and can contribute to informed decision-making in regulatory and risk assessment processes without the use of animals.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Mitochondrial Diseases
/
Adverse Outcome Pathways
Type of study:
Prognostic_studies
/
Risk_factors_studies
Limits:
Humans
Language:
En
Journal:
ALTEX
Journal subject:
MEDICINA
Year:
2024
Type:
Article
Affiliation country:
Belgium