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A mitochondrial EglN1-AMPKα axis drives breast cancer progression by enhancing metabolic adaptation to hypoxic stress.
Jiang, Weiwei; Zhang, Mengyao; Gao, Chuan; Yan, Chaojun; Gao, Ronghui; He, Ziwei; Wei, Xin; Xiong, Jingjing; Ruan, Zilun; Yang, Qian; Li, Jinpeng; Li, Qifang; Zhong, Ziyi; Zhang, Mengna; Yuan, Qianqian; Hu, Hankun; Wang, Shuang; Hu, Ming-Ming; Cai, Cheguo; Wu, Gao-Song; Jiang, Chao; Zhang, Ya-Lin; Zhang, Chen-Song; Zhang, Jing.
Affiliation
  • Jiang W; Department of Thyroid and Breast Surgery, Medical Research Institute, Frontier Science Center for Immunology and Metabolism, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
  • Zhang M; Department of Thyroid and Breast Surgery, Medical Research Institute, Frontier Science Center for Immunology and Metabolism, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
  • Gao C; Department of Thyroid and Breast Surgery, Medical Research Institute, Frontier Science Center for Immunology and Metabolism, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
  • Yan C; Department of Thyroid and Breast Surgery, Medical Research Institute, Frontier Science Center for Immunology and Metabolism, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
  • Gao R; Department of Thyroid and Breast Surgery, Medical Research Institute, Frontier Science Center for Immunology and Metabolism, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
  • He Z; Department of Thyroid and Breast Surgery, Medical Research Institute, Frontier Science Center for Immunology and Metabolism, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
  • Wei X; Life Sciences Institute, Zhejiang University, Hangzhou, China.
  • Xiong J; Department of Thyroid and Breast Surgery, Medical Research Institute, Frontier Science Center for Immunology and Metabolism, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
  • Ruan Z; Frontier Science Center for Immunology and Metabolism, Wuhan University, Wuhan, China.
  • Yang Q; Department of Thyroid and Breast Surgery, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
  • Li J; Department of Thyroid and Breast Surgery, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
  • Li Q; Department of Thyroid and Breast Surgery, Medical Research Institute, Frontier Science Center for Immunology and Metabolism, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
  • Zhong Z; Department of Thyroid and Breast Surgery, Medical Research Institute, Frontier Science Center for Immunology and Metabolism, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
  • Zhang M; Department of Thyroid and Breast Surgery, Medical Research Institute, Frontier Science Center for Immunology and Metabolism, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
  • Yuan Q; Department of Thyroid and Breast Surgery, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
  • Hu H; Department of Pharmacy, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, China.
  • Wang S; Mabnus Biological Technology Incorporation, Wuhan, China.
  • Hu MM; Frontier Science Center for Immunology and Metabolism, Wuhan University, Wuhan, China.
  • Cai C; Department of Thyroid and Breast Surgery, Medical Research Institute, Frontier Science Center for Immunology and Metabolism, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
  • Wu GS; Department of Thyroid and Breast Surgery, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
  • Jiang C; Life Sciences Institute, Zhejiang University, Hangzhou, China.
  • Zhang YL; State Key Laboratory for Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Fujian, China.
  • Zhang CS; State Key Laboratory for Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Fujian, China.
  • Zhang J; Department of Thyroid and Breast Surgery, Medical Research Institute, Frontier Science Center for Immunology and Metabolism, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
EMBO J ; 42(20): e113743, 2023 10 16.
Article in En | MEDLINE | ID: mdl-37661833
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / AMP-Activated Protein Kinases Type of study: Prognostic_studies Limits: Female / Humans Language: En Journal: EMBO J Year: 2023 Type: Article Affiliation country: China
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / AMP-Activated Protein Kinases Type of study: Prognostic_studies Limits: Female / Humans Language: En Journal: EMBO J Year: 2023 Type: Article Affiliation country: China