Outcomes in older kidney recipients from older donors: A propensity score analysis.
Front Nephrol
; 2: 1034182, 2022.
Article
in En
| MEDLINE
| ID: mdl-37675023
ABSTRACT
Background:
The age of patients referred for kidney transplantation has increased progressively. However, the precise influence of age on transplant outcomes is controversial.Methods:
Etrospective study in which graft and recipient survival were assessed in a cohort of ≥75 years old kidney recipients and compared with a contemporary younger one aged 60-65 years through a propensity score analysis.Results:
We included 106 recipients between 60-65 and 57 patients of ≥75 years old with a median follow-up of 31 [13-54] months. Unadjusted one- and five-year recipient survival did not significantly differ between the older (91% and 74%) and the younger group (95% and 82%, P=0.06). In the IPTW weighted Cox regression analysis, recipient age was not associated with an increased risk of death (HR 1.88 95%CI [0.81-4.37], P=0.14). Unadjusted one- and five-year death-censored graft survival did not significantly differ between both groups (96% and 83% for the older and 99% and 89% for the younger group, respectively, P=0.08). After IPTW weighted Cox Regression analysis, recipient age ≥75 years was no associated with an increased risk of graft loss (HR 1.95, 95%CI [0.65-5.82], P=0.23).Conclusions:
These results suggest that recipient age should not be considered itself as an absolute contraindication for kidney transplant.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Front Nephrol
Year:
2022
Type:
Article
Affiliation country:
Spain