Resuscitation, survival and morbidity of extremely preterm infants in California 2011-2019.
J Perinatol
; 44(2): 209-216, 2024 Feb.
Article
in En
| MEDLINE
| ID: mdl-37689808
ABSTRACT
OBJECTIVE:
To describe changes over time in resuscitation, survival, and morbidity of extremely preterm infants in California. STUDYDESIGN:
This population-based, retrospective cohort study includes infants born ≤28 weeks. Linked birth certificates and hospital discharge records were used to evaluate active resuscitation, survival, and morbidity across two epochs (2011-2014, 2015-2019).RESULTS:
Of liveborn infants, 0.6% were born ≤28 weeks. Active resuscitation increased from 16.9% of 22-week infants to 98.1% of 25-week infants and increased over time in 22-, 23-, and 25-week infants (p-value ≤ 0.01). Among resuscitated infants, survival to discharge increased from 33.2% at 22 weeks to 96.1% at 28 weeks. Survival without major morbidity improved over time for 28-week infants (p-value < 0.01).CONCLUSION:
Among infants ≤28 weeks, resuscitation and survival increased with gestational age and morbidity decreased. Over time, active resuscitation of periviable infants and morbidity-free survival of 28-week infants increased. These trends may inform counseling around extremely preterm birth.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Premature Birth
/
Infant, Premature, Diseases
Type of study:
Observational_studies
Limits:
Female
/
Humans
/
Infant
/
Newborn
Language:
En
Journal:
J Perinatol
Journal subject:
PERINATOLOGIA
Year:
2024
Type:
Article
Affiliation country:
United States