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A single-cell atlas of CD19 chimeric antigen receptor T cells.
Li, Xubin; Henderson, Jared; Gordon, Max J; Sheikh, Irtiza; Nastoupil, Loretta J; Westin, Jason; Flowers, Christopher; Ahmed, Sairah; Wang, Linghua; Neelapu, Sattva S; Strati, Paolo; Deng, Qing; Green, Michael R.
Affiliation
  • Li X; Department of Lymphoma & Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Henderson J; Department of Lymphoma & Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Gordon MJ; Department of Lymphoma & Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Sheikh I; Department of Pediatrics, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Nastoupil LJ; Department of Lymphoma & Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Westin J; Department of Lymphoma & Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Flowers C; Department of Lymphoma & Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Ahmed S; Department of Lymphoma & Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Wang L; Department of Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Neelapu SS; Department of Lymphoma & Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Strati P; Department of Lymphoma & Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Deng Q; Department of Lymphoma & Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address: qdeng1@mdanderson.org.
  • Green MR; Department of Lymphoma & Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address: mgreen5@mdanderson.org.
Cancer Cell ; 41(11): 1835-1837, 2023 11 13.
Article in En | MEDLINE | ID: mdl-37738975
ABSTRACT
Li et al. present a resource of single-cell RNA sequencing (scRNA-seq) data from the infusion products of relapsed or refractory large B cell lymphoma (rrLBCL) patients treated with standard-of-care axicabtagene ciloleucel and identify features that are significantly different between products from responders and non-responders at 3-month followup by PET/CT, an important landmark for long-term outcomes.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphoma, Large B-Cell, Diffuse / Receptors, Chimeric Antigen Limits: Humans Language: En Journal: Cancer Cell Journal subject: NEOPLASIAS Year: 2023 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphoma, Large B-Cell, Diffuse / Receptors, Chimeric Antigen Limits: Humans Language: En Journal: Cancer Cell Journal subject: NEOPLASIAS Year: 2023 Type: Article Affiliation country: United States