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Shared and unique antibody and B cell profiles in HIV-positive and HIV-negative individuals with cryptococcal meningoencephalitis.
Yoon, Hyunah; Nakouzi, Antonio S; Duong, Van Anh; Hung, Le Quoc; Binh, Tran Quang; Tung, Nguyen Le Nhu; Day, Jeremy N; Pirofski, Liise-Anne.
Affiliation
  • Yoon H; Division of Infectious Diseases, Department of Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York 10461, USA.
  • Nakouzi AS; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York 10461, USA.
  • Duong VA; Oxford University Clinical Research Unit, 764 Vo Van Kiet, Ho Chi Minh City Q5, Vietnam.
  • Hung LQ; Department of Tropical Diseases, Cho Ray Hospital, Ho Chi Minh City, Vietnam.
  • Binh TQ; Department of Tropical Diseases, Cho Ray Hospital, Ho Chi Minh City, Vietnam.
  • Tung NLN; Hospital for Tropical Diseases, 764 Vo Van Kiet, Ho Chi Minh City Q5, Vietnam.
  • Day JN; Oxford University Clinical Research Unit, 764 Vo Van Kiet, Ho Chi Minh City Q5, Vietnam.
  • Pirofski LA; Department of Microbiology and Infection, Royal Devon and Exeter Hospital, Exeter EX2 5DW, UK.
Med Mycol ; 61(10)2023 Oct 05.
Article in En | MEDLINE | ID: mdl-37771088
Unlike cryptococcal meningitis (CM) in HIV-positive individuals, there are no known biomarkers of risk in HIV-negative individuals and the diagnosis is often not suspected and delayed. This study identified non-T cells, including antibody and B cell CM-associated profiles that may guide cryptococcal antigen testing in HIV-negative individuals.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / Meningitis, Cryptococcal / Cryptococcus neoformans / Meningoencephalitis Type of study: Observational_studies / Risk_factors_studies Limits: Humans Language: En Journal: Med Mycol Journal subject: MEDICINA VETERINARIA / MICROBIOLOGIA Year: 2023 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / Meningitis, Cryptococcal / Cryptococcus neoformans / Meningoencephalitis Type of study: Observational_studies / Risk_factors_studies Limits: Humans Language: En Journal: Med Mycol Journal subject: MEDICINA VETERINARIA / MICROBIOLOGIA Year: 2023 Type: Article Affiliation country: United States