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Second-site suppressor mutations reveal connection between the drug-binding pocket and nucleotide-binding domain 1 of human P-glycoprotein (ABCB1).
Murakami, Megumi; Sajid, Andaleeb; Lusvarghi, Sabrina; Durell, Stewart R; Abel, Biebele; Vahedi, Shahrooz; Golin, John; Ambudkar, Suresh V.
Affiliation
  • Murakami M; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
  • Sajid A; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
  • Lusvarghi S; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
  • Durell SR; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
  • Abel B; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
  • Vahedi S; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
  • Golin J; Department of Biology, Catholic University of America, Washington, DC 20064, USA.
  • Ambudkar SV; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA. Electronic address: ambudkar@mail.nih.gov.
Drug Resist Updat ; 71: 101009, 2023 Nov.
Article in En | MEDLINE | ID: mdl-37797431
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Suppression, Genetic / Neoplasms Limits: Humans Language: En Journal: Drug Resist Updat Journal subject: ANTINEOPLASICOS Year: 2023 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Suppression, Genetic / Neoplasms Limits: Humans Language: En Journal: Drug Resist Updat Journal subject: ANTINEOPLASICOS Year: 2023 Type: Article Affiliation country: United States