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A synthetic resveratrol-curcumin hybrid derivative exhibits chemopreventive effects on colon pre-neoplastic lesions by targeting Wnt/ß-catenin signaling, anti-inflammatory and antioxidant pathways.
Baptistella, Mariane Minussi; Assunção, Raphaela Rebeca Silveira; Sales de Oliveira, Carolina; Siqueira, Aléxia Polo; Gonçalves Dos Santos, Elda; de Freitas Silva, Matheus; Lima, Ellen Tardelli Faleiros; Caixeta, Ester Siqueira; Novaes, Rômulo Dias; Ferreira, Eric Batista; Ionta, Marisa; Viegas, Claudio; Francielli de Oliveira, Pollyanna.
Affiliation
  • Baptistella MM; Institute of Natural Sciences, Federal University of Alfenas, 37130-000, Minas Gerais, Brazil.
  • Assunção RRS; Institute of Natural Sciences, Federal University of Alfenas, 37130-000, Minas Gerais, Brazil.
  • Sales de Oliveira C; Institute of Natural Sciences, Federal University of Alfenas, 37130-000, Minas Gerais, Brazil.
  • Siqueira AP; Institute of Natural Sciences, Federal University of Alfenas, 37130-000, Minas Gerais, Brazil.
  • Gonçalves Dos Santos E; Institute of Biomedical Sciences, Federal University of Alfenas, 37130-000, Minas Gerais, Brazil.
  • de Freitas Silva M; Institute of Chemistry, Laboratory of Research in Medicinal Chemistry, Federal University of Alfenas, 37133-840, Minas Gerais, Brazil.
  • Lima ETF; Institute of Chemistry, Laboratory of Research in Medicinal Chemistry, Federal University of Alfenas, 37133-840, Minas Gerais, Brazil.
  • Caixeta ES; Institute of Biomedical Sciences, Federal University of Alfenas, 37130-000, Minas Gerais, Brazil.
  • Novaes RD; Institute of Biomedical Sciences, Federal University of Alfenas, 37130-000, Minas Gerais, Brazil.
  • Ferreira EB; Institute of Exact Sciences, Federal University of Alfenas, 37130-000, Minas Gerais, Brazil.
  • Ionta M; Institute of Biomedical Sciences, Federal University of Alfenas, 37130-000, Minas Gerais, Brazil.
  • Viegas C; Institute of Chemistry, Laboratory of Research in Medicinal Chemistry, Federal University of Alfenas, 37133-840, Minas Gerais, Brazil.
  • Francielli de Oliveira P; Institute of Natural Sciences, Federal University of Alfenas, 37130-000, Minas Gerais, Brazil.
J Pharm Pharmacol ; 2023 Oct 24.
Article in En | MEDLINE | ID: mdl-37874746
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: J Pharm Pharmacol Year: 2023 Type: Article Affiliation country: Brazil
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: J Pharm Pharmacol Year: 2023 Type: Article Affiliation country: Brazil