Refractory Microascus Bronchopulmonary Infection Treated with Olorofim, France.

Faure, Emmanuel; Brugière, Olivier; de Verdiere, Sylvie Colin; Vuotto, Fanny; Limousin, Lucie; Cardot, Emilie; Cordier, Camille; Coulon, Pauline; Garcia-Hermoso, Dea; Lortholary, Olivier; Lanternier, Fanny

Faure, Emmanuel; Brugière, Olivier; de Verdiere, Sylvie Colin; Vuotto, Fanny; Limousin, Lucie; Cardot, Emilie; Cordier, Camille; Coulon, Pauline; Garcia-Hermoso, Dea; Lortholary, Olivier; Lanternier, Fanny.

Emerg Infect Dis ; 29(11): 2401-2403, 2023 11.

Article in En | MEDLINE | ID: mdl-37877687

ABSTRACT

ABSTRACT

We report 3 cases of successful treatment of Microascus spp. bronchopulmonary infection in a multiple-traumatized patient and 2 lung transplant recipients in France. We emphasize the promising use of olorofim antifungal therapy in a rising context of intrinsically less-susceptible respiratory infections caused by mold.

Subject(s)

Ascomycota; Humans; Piperazines; Pyrimidines; Acetamides; Antifungal Agents/therapeutic use

Key words

France; M. cirrosus pneumonia; Microascus; Microascus melanosporus; fungi; olorofim; respiratory infections

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ascomycota Limits: Humans Language: En Journal: Emerg Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2023 Type: Article

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