Modification of astrocytic Cx43 hemichannel activity in animal models of AD: modulation by adenosine A<sub>2A</sub> receptors.

Madeira, Daniela; Domingues, Joana; Lopes, Cátia R; Canas, Paula M; Cunha, Rodrigo A; Agostinho, Paula

Modification of astrocytic Cx43 hemichannel activity in animal models of AD: modulation by adenosine A_2A receptors.

Madeira, Daniela; Domingues, Joana; Lopes, Cátia R; Canas, Paula M; Cunha, Rodrigo A; Agostinho, Paula.

Affiliation

Madeira D; Faculty of Medicine, University of Coimbra (FMUC), Coimbra, Portugal.
Domingues J; Center for Neuroscience and Cell Biology (CNC), University of Coimbra, Rua Larga, Polo I FMUC, First Floor, 3004-504, Coimbra, Portugal.
Lopes CR; Center for Neuroscience and Cell Biology (CNC), University of Coimbra, Rua Larga, Polo I FMUC, First Floor, 3004-504, Coimbra, Portugal.
Canas PM; Faculty of Medicine, University of Coimbra (FMUC), Coimbra, Portugal.
Cunha RA; Center for Neuroscience and Cell Biology (CNC), University of Coimbra, Rua Larga, Polo I FMUC, First Floor, 3004-504, Coimbra, Portugal.
Agostinho P; Center for Neuroscience and Cell Biology (CNC), University of Coimbra, Rua Larga, Polo I FMUC, First Floor, 3004-504, Coimbra, Portugal.

Cell Mol Life Sci ; 80(11): 340, 2023 Oct 29.

Article in En | MEDLINE | ID: mdl-37898985

Subject(s)

Alzheimer Disease; Mice; Animals; Alzheimer Disease/metabolism; Astrocytes/metabolism; Connexin 43/genetics; Connexin 43/metabolism; Adenosine/metabolism; Amyloid beta-Peptides/metabolism; Disease Models, Animal

Key words

Adenosine A2A receptors; Alzheimer's disease; Astrocytes; Connexin 43; Hemichannels

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alzheimer Disease Limits: Animals Language: En Journal: Cell Mol Life Sci Journal subject: BIOLOGIA MOLECULAR Year: 2023 Type: Article Affiliation country: Portugal

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