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A Practical Guide to the Pearls and Pitfalls of PSMA PET Imaging.
Voter, Andrew F; Werner, Rudolf A; Savas, Hatice; Gafita, Andrei; Ross, Ashley E; Gorin, Michael A; Solnes, Lilja B; Pomper, Martin G; Rowe, Steven P; Sheikhbahaei, Sara.
Affiliation
  • Voter AF; The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Werner RA; Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany.
  • Savas H; Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, IL.
  • Gafita A; The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Ross AE; Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, IL.
  • Gorin MA; Milton and Carroll Petrie Department of Urology, Icahn School of Medicine at Mount Sinai, New York, NY.
  • Solnes LB; The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Pomper MG; The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Rowe SP; Department of Radiology, University of North Carolina, Chapel Hill, NC. Electronic address: Steven_rowe@med.unc.edu.
  • Sheikhbahaei S; The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD.
Semin Nucl Med ; 54(1): 119-131, 2024 01.
Article in En | MEDLINE | ID: mdl-37980186
ABSTRACT
Prostate-specific membrane antigen (PSMA)-targeted PET agents have revolutionized the care of patients with prostate cancer, supplanting traditional methods of imaging prostate cancer, and improving the selection and delivery of therapies. This has led to a rapid expansion in both the number of PSMA PET scans performed and the imaging specialists required to interpret those scans. To aid those imagers and clinicians who are new to the interpretation of PSMA PET, this review provides an overview of the interpretation of PSMA PET/CT imaging and pearls for overcoming commonly encountered pitfalls. We discuss the physiologic distribution of the clinically available PSMA-targeted radiotracers, the commonly encountered patterns of prostate cancer spread, as well as the benign and malignant mimics of prostate cancer. Additionally, we review the standardized PSMA PET reporting systems and the role of PSMA in selecting appropriate patients for PSMA-targeted therapies.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Positron Emission Tomography Computed Tomography Limits: Humans / Male Language: En Journal: Semin Nucl Med Year: 2024 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Positron Emission Tomography Computed Tomography Limits: Humans / Male Language: En Journal: Semin Nucl Med Year: 2024 Type: Article