Downhill running and caloric restriction attenuate insulin resistance associated skeletal muscle atrophy via the promotion of M2-like macrophages through TRIB3-AKT pathway.

Luo, Wei; Zhou, Yue; Tang, Qiang; Wang, Yuhang; Liu, Yansong; Ai, Lei

Luo, Wei; Zhou, Yue; Tang, Qiang; Wang, Yuhang; Liu, Yansong; Ai, Lei.

Affiliation

Luo W; Department of Sports and Health Sciences, Nanjing Sport Institute, Nanjing, China.
Zhou Y; Department of Exercise Physiology, Beijing Sport University, Beijing, China.
Tang Q; Department of Sports and Health Sciences, Nanjing Sport Institute, Nanjing, China.
Wang Y; Department of Sports and Health Sciences, Nanjing Sport Institute, Nanjing, China.
Liu Y; Department of Sports and Health Sciences, Nanjing Sport Institute, Nanjing, China.
Ai L; Jiangsu Research Institute of Sports Science, Nanjing, China. Electronic address: ailei_982@163.com.

Free Radic Biol Med ; 210: 271-285, 2024 01.

Article in En | MEDLINE | ID: mdl-38036069

Subject(s)

Insulin Resistance; Running; Mice; Animals; Insulin Resistance/physiology; Proto-Oncogene Proteins c-akt/genetics; Proto-Oncogene Proteins c-akt/metabolism; Caloric Restriction; Muscular Atrophy/genetics; Muscular Atrophy/metabolism; Muscle, Skeletal/metabolism; Macrophages/metabolism; Diet, High-Fat/adverse effects; Mice, Inbred C57BL

Key words

Downhill running; Insulin resistance; Macrophage polarization; Skeletal muscle atrophy; TRIB3-AKT pathway

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Running / Insulin Resistance Limits: Animals Language: En Journal: Free Radic Biol Med Journal subject: BIOQUIMICA / MEDICINA Year: 2024 Type: Article Affiliation country: China

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