USP43 impairs cisplatin sensitivity in epithelial ovarian cancer through HDAC2-dependent regulation of Wnt/ß-catenin signaling pathway.

Pei, Lipeng; Zhao, Feng; Zhang, Yi

Pei, Lipeng; Zhao, Feng; Zhang, Yi.

Affiliation

Pei L; Department of Obstetrics and Gynecology, General Hospital of Northern Theater Command, Shenyang, People's Republic of China.
Zhao F; Department of Stem Cells and Regenerative Medicine, College of Basic Medical Science, China Medical University, Shenyang, People's Republic of China.
Zhang Y; Department of Gynecology, The First Hospital of China Medical University, No. 155, Nanjing North Street, Shenyang, People's Republic of China. Syzi@163.com.

Apoptosis ; 29(1-2): 210-228, 2024 Feb.

Article in En | MEDLINE | ID: mdl-38087046

Subject(s)

Cisplatin; Ovarian Neoplasms; Humans; Female; Carcinoma, Ovarian Epithelial/drug therapy; Carcinoma, Ovarian Epithelial/genetics; Carcinoma, Ovarian Epithelial/pathology; Cisplatin/pharmacology; Wnt Signaling Pathway; beta Catenin/genetics; beta Catenin/metabolism; Apoptosis; Ovarian Neoplasms/drug therapy; Ovarian Neoplasms/genetics; Ovarian Neoplasms/metabolism; Cell Proliferation; Gene Expression Regulation, Neoplastic; Cell Line, Tumor; Histone Deacetylase 2/genetics; Histone Deacetylase 2/metabolism

Key words

Cisplatin sensitivity; Epithelial ovarian cancer; HDAC2; USP43; Wnt/ß-catenin signaling pathway

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Cisplatin Limits: Female / Humans Language: En Journal: Apoptosis Year: 2024 Type: Article

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